RecruitingNCT06341933

Risk Factors for AKI in Patients Undergoing VATS for Pulmonary Resection

Risk Factors for Acute Kidney Injury in Patients Undergoing Video-Assisted Thoracoscopic Surgery for Pulmonary Resection: A Prospective Observational Study


Sponsor

Atatürk Chest Diseases and Chest Surgery Training and Research Hospital

Enrollment

100 participants

Start Date

Apr 15, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

This study aims to investigate the potential factors contributing to the development of Acute Kidney Injury (AKI) in patients undergoing pulmonary resection with Video Assisted Thoracoscopic Surgery (VATS) for lung malignancy. The study will focus on demographic data, laboratory parameters, perioperative fluid management, and haemodynamics. The research will be conducted at SBÜ Ankara Atatürk Sanatorium Training and Research Hospital. The study will involve patients who have given informed consent and will undergo VATS with standard anaesthesia monitoring. Anaesthesia management will follow our routine protocol in our clinic. Patients will be divided into two groups based on whether they have a more than 25% decrease in estimated glomerular filtration rate (t-GFH) and/or a 1.5-fold increase in serum creatinine and/or a 6-hour urine volume of less than 0.5 ml/kg/h. The patients will be divided into two groups based on this definition, and the risk factors between these groups will be analysed. The preoperative routine blood values, demographic data (age, gender, height, weight, and BMI), ASA physical status, smoking and alcohol habits, comorbidities, and regular medication use will be recorded. Intraoperative urine output and haemodynamic parameters will also be monitored. Routine blood gas analysis, blood urea nitrogen (BUN), glomerular filtration rate (GFR), albumin, haemoglobin, sodium, potassium, chlorine, and magnesium will be measured and recorded, along with urine output and t-GFH. Patients will be evaluated in the hospital on the day the surgeon calls for a postoperative check-up and on the 30th postoperative day to see if there are any complications.


Eligibility

Min Age: 18 YearsMax Age: 65 Years

Plain Language Summary

Simplified for easier understanding

This observational study collects data to identify which patients undergoing minimally invasive lung surgery (called VATS — video-assisted thoracoscopic surgery) are at highest risk of developing acute kidney injury (sudden loss of kidney function) after the procedure. **You may be eligible if...** - You are between 18 and 65 years old - You are scheduled for elective minimally invasive lung surgery (VATS) to remove a portion of a lung due to a malignancy (wedge, segmental, or lobe removal) - Your general health status is ASA class 1–3 **You may NOT be eligible if...** - Your BMI is below 18.5 or above 35 kg/m² - You already have reduced kidney function (elevated creatinine beyond defined thresholds) - You received contrast dye for imaging in the preoperative period - You have heart failure or a history of pulmonary edema - You have used steroids or anti-inflammatory drugs for more than 30 days - You require intensive care before surgery Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

OTHERDuration of Surgery

Total surgery time in minutes

OTHERVolume of Fluid in Surgery

Fluid volume given during surgery in ml

OTHERBlood Loss

Blood loss during surgery in ml


Locations(1)

Ankara Atatürk Sanatorium Training and Research Hospital

Ankara, Keçiören, Turkey (Türkiye)

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT06341933


Related Trials