RecruitingNCT06341985

DOsimetry and Radiation Induced NAusea in Head and Neck Cancers

Prospective Multicenter Cohort Study for the Analysis of Correlation Between Dosimetric Parameters and RANV (Radiation Associated Nausea and Vomiting) in Patients With Head and Neck Cancer Undergoing Exclusive Radiotherapy (RT)


Sponsor

European Institute of Oncology

Enrollment

180 participants

Start Date

Nov 15, 2021

Study Type

OBSERVATIONAL

Conditions

Summary

This is a prospective cohort study for the analysis of correlation between dosimetric parameters and RANV (Radiation Associated Nausea and Vomiting) in patients with head and neck cancer undergoing exclusive radiotherapy (RT). The primary purpose of this study is to search for a potential correlation between dosimetry and physician- and patient-rated symptoms in patients treated with exclusive radiotherapy for head and neck cancer.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study examines the relationship between the radiation dose delivered to specific areas of the brain and the severity of nausea experienced during radiation therapy for head and neck cancers. The goal is to identify which brain areas, when exposed to radiation, cause the most nausea so future treatments can better avoid them. **You may be eligible if...** - You are 18 or older - You have been diagnosed with a primary head and neck cancer (including oropharynx, nasopharynx, mouth, salivary glands, or sinuses) - You are receiving curative radiation therapy with modern techniques (IMRT, VMAT, proton therapy, or similar) - You are willing to provide clinical data for the study **You may NOT be eligible if...** - Your cancer is not a primary head and neck tumor - You are not receiving radiation with curative intent - You are unwilling or unable to have data collected Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

RADIATIONExclusive radiotherapy

Curative radiotherapy treatment using 3D conformal or Intensity Modulated Radiation Therapy (IMRT) techniques.


Locations(14)

Azienda Ospedaliero Universitaria Ospedali Riuniti di Ancona

Ancona, Italy

Ospedale "Mons. Dimiccoli"

Barletta, Italy

Azienda Ospedaliera S.Pio

Benevento, Italy

Ospedale MultiMedica

Castellanza, Italy

IRCCS Ospedale Policlinico San Martino

Genova, Italy

Azienda Ospedaliero-Universitaria di Modena

Modena, Italy

Azienda Ospedaliero Universitaria Ospedale Maggiore della Carità di Novara

Novara, Italy

Fondazione IRCCS Policlinico San Matteo

Pavia, Italy

Azienda Ospedaliera Complesso Ospedaliero San Giovanni - Addolorata

Roma, Italy

Azienda Ospedaliero Universitaria Policlinico Umberto I

Roma, Italy

Ospedale San Giovanni Calibita Fatebenefratelli Isola Tiberina

Roma, Italy

I.R.C.C.S. MultiMedica - Sesto San Giovanni

Sesto San Giovanni, Italy

European Institute of Oncology

Milan, Italy

IRCCS Ospedale San Raffaele

Milan, Italy

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT06341985


Related Trials