Head and Neck Neoplasm Clinical Trials

2 recruiting

Frequently Asked Questions

Common questions about Head and Neck Neoplasm clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 32 trials

Recruiting

The MOMENTUM Study: The Multiple Outcome Evaluation of Radiation Therapy Using the MR-Linac Study

Breast CancerLiver CancerEsophageal Cancer+35 more
UMC Utrecht8,000 enrolled18 locationsNCT04075305
Recruiting
Phase 2

A Study of Decreasing Radiation Therapy and Chemotherapy in People With Head and Neck Cancer

Head and Neck CarcinomaHead and Neck CancerHead and Neck Squamous Cell Carcinoma+1 more
Memorial Sloan Kettering Cancer Center12 enrolled6 locationsNCT05544136
Recruiting
Phase 1

First in Human Study of AZD9592 in Solid Tumors

Carcinoma, Non-Small Cell LungColorectal NeoplasmsHead and Neck Neoplasms+1 more
AstraZeneca403 enrolled50 locationsNCT05647122
Recruiting

Circulating Tumor DNA (ctDNA) in Locally Advanced Head and Neck Squamous Cell Carcinoma

Carcinoma, Squamous CellHead and Neck Neoplasm
UNC Lineberger Comprehensive Cancer Center50 enrolled1 locationNCT04099290
Recruiting
Phase 2

Heavy Strength Training in Head and Neck Cancer Survivors

Head and Neck CarcinomaHead and Neck CancerHead and Neck Squamous Cell Carcinoma+1 more
University of Alberta60 enrolled1 locationNCT06289049
Recruiting
Not Applicable

Association Between Health Care Provider (HCP)-Assessed ECOG Performance Status (PS) and Overall Survival, and Objectively Measure of Physical Activity (PA) Levels in Advance-cancer Patients"

Stage I Colorectal Cancer AJCC v6 and v7Stage II Colorectal Cancer AJCC v7Stage III Colorectal Cancer AJCC v7+45 more
M.D. Anderson Cancer Center590 enrolled1 locationNCT01365169
Recruiting
Not Applicable

Photobiomodulation Therapy Plus M-health in Head and Neck Cancer Patients: LAXER Study

Head and Neck CancerHead and Neck NeoplasmsXerostomia
Universidad de Granada60 enrolled1 locationNCT05106608
Recruiting
Phase 3

Head and Neck Cancer Study Project in the Geriatric Population

Head and Neck Neoplasms
Brown University20 enrolled1 locationNCT06998069
Recruiting
Phase 2

A Study of Pembrolizumab in Combination With Chemotherapy for Head and Neck Cancer

Head and Neck CancerHead and Neck Squamous Cell CarcinomaHead and Neck Neoplasms+2 more
University of Chicago30 enrolled1 locationNCT05420948
Recruiting
Phase 1

Dose Finding Study of Zanzalintinib With Pembrolizumab and Cetuximab in Head and Neck SCC

Head and Neck NeoplasmsNeoplasm MetastasisCarcinoma, Squamous Cell+3 more
University of Chicago36 enrolled1 locationNCT06912087
Recruiting

NIDCD Otolaryngology Clinical Protocol Biospecimen Bank

Head and Neck NeoplasmsHearing LossHearing Disorders+1 more
National Institute on Deafness and Other Communication Disorders (NIDCD)1,000 enrolled1 locationNCT06303180
Recruiting
Phase 4

DPYD Pharmacogenomics and Fluoropyrimidine (FP) Dose-Adjustment

Breast NeoplasmsColorectal NeoplasmsHead and Neck Neoplasms+1 more
Rutgers, The State University of New Jersey100 enrolled12 locationsNCT07158164
Recruiting

Oropharynx (OPX) Biomarker Trial

Head and Neck CarcinomaClinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8+8 more
Mayo Clinic440 enrolled1 locationNCT06356272
Recruiting
Phase 1

Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid Tumors

Colorectal, CancerSquamous Cell Carcinoma of Head and NeckHead and Neck Squamous Cell Carcinoma+8 more
Bicara Therapeutics292 enrolled20 locationsNCT04429542
Recruiting

Biospecimen Procurement for Head and Neck Disorders

Head and Neck NeoplasmsLaryngeal DiseaseHearing Disorder+2 more
National Cancer Institute (NCI)1,000 enrolled9 locationsNCT03429036
Recruiting

The EMINENCE Study - PET/MR Imaging of Head Neck Cancer

Head and Neck Neoplasms
Norwegian University of Science and Technology390 enrolled2 locationsNCT04612075
Recruiting
Phase 1Phase 2

HTL0039732 in Participants With Advanced Solid Tumours

SarcomaUrinary Bladder NeoplasmsUterine Cervical Neoplasms+11 more
Cancer Research UK150 enrolled5 locationsNCT05944237
Recruiting
Not Applicable

The SNAP Tool for Head and Neck Cancer Survivor-Caregiver Dyads

Head and Neck CancerSurvivorshipHead and Neck Neoplasms+1 more
Medical University of South Carolina352 enrolled1 locationNCT05811936
Recruiting
Phase 2

Open Label Phase 2 Basket Trial With Atezolizumab and Tiragolumab in Solid Tumors

MelanomaHead and Neck NeoplasmsMSI-H Cancer
University Medical Center Groningen97 enrolled1 locationNCT05483400
Recruiting
Phase 3

Upfront Surgery Vs Induction Chemotherapy Followed By Surgery In Oral Cancers:

Head and Neck NeoplasmsOral Cancer
All India Institute of Medical Sciences, Jodhpur346 enrolled7 locationsNCT06737822