RecruitingNCT06359808

Clinical Characteristics of Sleep Disorders in Patients With Ulcerative Colitis

A Study Based on the Microbiota-gut-brain Axis to Explore the Clinical Characteristics of Sleep Disorders in Patients With Ulcerative Colitis


Sponsor

Xijing Hospital

Enrollment

152 participants

Start Date

Apr 1, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

Ulcerative colitis(UC) is one of the two main forms of inflammatory bowel disease(IBD), which seriously affects the quality of life of patients. Previous studies have demonstrated that more than 60% of IBD patients have sleep disorders, which is emerging as an important risk factor for disease recurrence and poor prognosis. However, the mechanisms by which sleep disorders regulates the occurrence and development of IBD remain undefined. This study aims to explore the clinical characteristics of ulcerative colitis patients with sleep disorders based on the microbiota-gut-brain axis, to analyze the effects of sleep disorders on autonomic nervous function, gut microbiota, and metabolites in UC patients.


Eligibility

Min Age: 18 YearsMax Age: 65 Years

Plain Language Summary

Simplified for easier understanding

This study is documenting the sleep problems experienced by patients with ulcerative colitis (a type of inflammatory bowel disease that causes chronic inflammation in the colon). It aims to understand how common sleep disorders are in this group and what factors contribute to them. **You may be eligible if...** - You have been diagnosed with ulcerative colitis according to standard Chinese medical guidelines - You have complete medical records and are willing to give informed consent **You may NOT be eligible if...** - You have a prior history of mental illness or are taking anti-anxiety or antidepressant medication - You have digestive system cancer or serious heart, lung, liver, or kidney disease - You have taken medications that affect heart rate or the nervous system (like beta-blockers or calcium channel blockers) in the past 2 weeks - You have consumed stimulants like cigarettes, alcohol, tea, or coffee in the past 24 hours Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(1)

Xijing Hospital

Xi'an, Shaanxi, China

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NCT06359808


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