RecruitingNot ApplicableNCT06363305

Impact of Sex in the Effect of Dietary Capsaicin on Cardiovascular Health

Impact of Sex in the Effect of Dietary Capsaicin on Cardiovascular Health: A Randomized Controlled Trial


Sponsor

Skidmore College

Enrollment

80 participants

Start Date

Jul 8, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The investigators long-term goal is to better understand novel interventions to promote cardiovascular health in humans. The goal of the proposed research is to investigate whether there is sex-specificity in the effects of dietary capsaicin on mechanisms regulating nitric oxide (NO) bioavailability, its effect on key markers of cardiovascular (CV) health, including BP, macro- and microvascular function, and arterial stiffness. This knowledge will provide critical insight into the effects of dietary capsaicin on CV health and will guide future trials.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study looks at whether eating capsaicin — the compound that makes chili peppers hot — affects heart health differently in men versus women. Participants will consume a capsaicin supplement daily and researchers will track blood pressure and other cardiovascular markers. **You may be eligible if...** - You are a man or woman over 18 years old - You are generally healthy, other than possibly having elevated blood pressure - You are a non-smoker **You may NOT be eligible if...** - You are a woman who has missed periods for non-medical reasons, or who is pregnant, trying to get pregnant, or breastfeeding - You have uncontrolled high blood pressure - You have a severe illness or a weakened immune system - You are very sensitive to spicy foods or fiber supplements - You have food allergies - You have difficulty swallowing - You suffer from heartburn or acid reflux that might be worsened by spicy foods Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIETARY_SUPPLEMENTDietary capsules

Daily doses of dietary capsaicin or placebo in capsule form


Locations(1)

Skidmore College

Saratoga Springs, New York, United States

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NCT06363305


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