Imaging Traumatic Stress and Alcohol Use Disorder With [18F]Bavarostat

This study uses a new brain imaging tracer called [18F]Bavarostat to examine how PTSD (post-traumatic stress disorder) and alcohol use disorder affect specific chemical pathways in the brain. The goal is to better understand the brain biology behind trauma and addiction. **You may be eligible if...** - You are between 18 and 70 years old - You have a current diagnosis of PTSD (based on DSM-5 criteria), OR a diagnosis of alcohol use disorder, OR you have experienced a traumatic event but don't have PTSD (as a comparison group) - You are in generally good health **You may NOT be eligible if...** - You have a serious current medical condition - You have other significant psychiatric diagnoses that would interfere - You are pregnant or breastfeeding - You are unable to undergo brain imaging (e.g., metal implants) Talk to your doctor to see if this trial is right for you.