RecruitingNot ApplicableNCT06383247

The Efficacy and Safety of Precision REpetitive Transcranial Magnetic Stimulation in Alleviating Motor Symptom in Parkinson's Disease

A Randomized, Double-blind, Multicenter, Placebo-controlled Trial (PRESS-PD)

Sponsor

Anhui Medical University

Enrollment

290 participants

Start Date

Dec 6, 2024

Study Type

INTERVENTIONAL

Conditions

Parkinson Disease Transcranial Magenetic Stimualtion Supplementary Motor Area

Summary

Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive and widely used neuromodulation technology. Small sample studies have shown that rTMS treatment can significantly improve the symptoms of Parkinson's disease(PD) and delay the progression of the disease. In order to further explore the effectiveness of rTMS in the treatment of PD and lay the foundation for its clinical promotion, our research team plans to conduct a randomized double-blind controlled study of rTMS in the treatment of PD in multiple centers across the country.

Eligibility

Min Age: 40 Years

Plain Language Summary

Simplified for easier understanding

This study is testing a type of non-invasive brain stimulation called repetitive transcranial magnetic stimulation (rTMS) — which uses magnetic pulses to stimulate specific brain areas — to help improve movement symptoms in people with Parkinson's disease. **You may be eligible if...** - You are 40 years or older - You have been diagnosed with idiopathic (standard) Parkinson's disease - Your Parkinson's medication has been stable for at least 4 weeks - You have moderate motor symptoms and are in an early-to-middle stage of the disease - You can cooperate with tests and treatments **You may NOT be eligible if...** - You have a brain injury, severe white matter damage, or have had brain surgery - You have metal implants (like a pacemaker or cochlear implant) - You have epilepsy or unexplained fainting - You are pregnant or planning to become pregnant - You have participated in another clinical trial in the past 6 months Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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