Obesity Management for Kidney TRANSPLANTation: OK-TRANSPLANT 2

This study tests a structured obesity management program — combining diet, lifestyle coaching, and possibly medication — to help kidney transplant candidates lose enough weight to become eligible for transplantation. **You may be eligible if...** - You have end-stage kidney disease and are being evaluated for a kidney transplant - You have a BMI (body mass index) that currently makes you ineligible or borderline for transplant listing - You are motivated and able to participate in a structured weight management program - You are at least 18 years old **You may NOT be eligible if...** - You have a contraindication to the weight management interventions being used (e.g., certain medications) - You have uncontrolled heart disease or other unstable medical conditions - You are pregnant or planning pregnancy during the study - You have already had a prior kidney transplant that failed due to non-immunological reasons Talk to your doctor to see if this trial is right for you.