RecruitingPhase 2NCT06401707

PeRampanel fOr Status ePilEpticus pRophylaxis Post-cardiac Arrest


Sponsor

University of California, San Francisco

Enrollment

52 participants

Start Date

May 20, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

Brain injury is the main cause of death and disability for patients surviving cardiac arrest resuscitation and seizures are diagnosed in up to a third of these patients. The investigators are proposing a pilot randomized placebo-controlled clinical trial to evaluate the safety and feasibility of perampanel use for post-cardiac arrest status epilepticus (PCARSE) prevention after cardiac arrest.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Perampanel and a drug called Placebo for people with heart arrest, seizures, and other related conditions. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGPerampanel

Perampanel is a non-competitive AMPA glutamate receptor antagonist.

DRUGPlacebo

Placebo


Locations(1)

Zuckerberg San Francisco General Hospital

San Francisco, California, United States

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NCT06401707


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