RecruitingNCT06408415

A Study of the Higher Cognitive Functions of the Human Brain With Single-neuron Activity Recording

A Study of the Higher Cognitive Functions of the Human Brain Based on the Use of Hyperflexible Neural Electrode-cortex for Single-neuron Activity Recording


Sponsor

Huashan Hospital

Enrollment

10 participants

Start Date

Jun 19, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

This study aims to investigate that neural activity of higher cognitve function of human brain with hyperflexible neural electrode-cortex


Eligibility

Min Age: 18 YearsMax Age: 70 Years

Inclusion Criteria4

  • aged 18-70 years old.
  • have selective or confine operation indications:spontaneous basal ganglia hemorrhage or lobar hemorrhage that need catheter aspiration and drainage;hydrocephalus that need V-P shunt; need placing ommaya.
  • GCS score 12-15; must be able to communicate with investigators in Mandarin and comply with study requirements.
  • volunteered to participate in this study and sign informed consent.

Exclusion Criteria10

  • have severe cognitive dysfunction.
  • have psychiatric disorders, such as depression, anxiety disorders and schizophrenia.
  • long-term use of special medications, such as hormones, immunosuppressant, and anticoagulants.
  • be allergic to surgery instruments or medications.
  • have general anesthesia, surgery contraindications.
  • have acute cardiac infarction or heart arrest within 6 months.
  • have other neurosurgery contraindications assessed by investigators.
  • lactation or pregnancy.
  • have serious systemic disease or organ dysfunctions that affects study outcome or visits.
  • participate in other ongoing clinical trials.

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Locations(1)

Department of Neurosurgery, Huashan Hospital, Fudan University

Shanghai, Shanghai Municipality, China

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NCT06408415


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