RecruitingNCT06412250

A Multicenter Observational Registry to Evaluate Safety and Performance of Vivo ISAR (SECURE Global Registry)

A Prospective, Open-Label, Multi-Country, Multicentre, Observational PoSt Market SurvEillance of VIVO ISAR (Polymer-Free Sirolimus Eluting Coronary Stent System) In Real World Patients Undergoing PCI With Short Dual Antiplatelet Therapy


Sponsor

Translumina Therapeutics Pvt Ltd.

Enrollment

2,000 participants

Start Date

Jan 10, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

The objective of this post marketing observational registry is to evaluate clinical outcomes (safety and performance) in an all-comers population with coronary artery disease (CAD) treated with the Polymer Free Sirolimus Eluting Coronary Stent Vivo ISAR and planned for an abbreviated (≤ 3 months) dual antiplatelet therapy (DAPT) regimen.


Eligibility

Min Age: 18 Years

Inclusion Criteria5

  • Ability to provide written informed consent.
  • Treated only with the VIVO ISAR stent system.
  • ≥ 18 years old.
  • Male or non-pregnant female patient.
  • Intended for treatment with ≤ 3 months DAPT after PCI as per standard of care.

Exclusion Criteria8

  • Patients having any of the following conditions will not be considered (enrolled) for the study Concurrent participation in an interventional study.
  • Cardiogenic shock/hemodynamic instability around the time of the index procedure.
  • Concurrent medical condition with a life expectancy of less than 12 months.
  • Allergy or contraindication to antiplatelet therapy, cobalt chromium, sirolimus or any known hypersensitivity to the planned anti-platelet drugs.
  • History of cerebrovascular accident in the last 6 months.
  • Pregnant female.
  • PCI performed within the previous 3 months from the date of index procedure
  • Treated with another stent type during the index procedure in addition to the VIVO ISAR stent system

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Locations(32)

Zydus Hospitals

Ahmedabad, India

Fortis Hospital

Bangalore, India

Adesh Hospital

Bathinda, India

PGIMER

Chandigarh, India

National Heart Institute

Delhi, India

Fortis Escorts Heart Institute & Research Centre

Delhi, India

Fortis Escorts Heart Institute & Research Centre

Delhi, India

Medanta-The Medicity

Gurugram, India

Yashoda Hospitals

Hyderabad, India

Shalby Hospital

Jabalpur, India

Fortis Hospital

Kalyān, India

L.P.S Institute of Cardiology

Kanpur, India

Fortis Hospital

Kolkata, India

Dr. Ram Manohar Lohia Hospital (RML)

Lucknow, India

Seva Sadan Hospital

Miraj, India

Fortis

Mohali, India

Yashodha Hospital

Somājigūda, India

ASREM - Regional Hospitals

Campobasso, Italy

Montevergine

Mercogliano AV, Italy

Clinica Mediterranea

Naples, Italy

University of Padua, Padova

Padova, Italy

Clinica Pierangeli

Pescara, Italy

Santo Spirito Hospital

Pescara, Italy

Tor Vergata University

Roma, Italy

Amsterdam UMC (University Medical Centers)

Amsterdam, Netherlands

Tergooi MC

Hilversum, Netherlands

Viecuri MC

Venlo, Netherlands

Bedford Hospital

Bedford, United Kingdom

Freeman Hospital

Newcastle, United Kingdom

Derriford Hospitalm Plymouth NHS Trust

Plymouth, United Kingdom

Salisbury NHS Foundation Trust

Salisbury, United Kingdom

Wrightington, Wigan and Leigh Teaching Hospitals NHS Foundation Trust

Wigan, United Kingdom

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