Study to Evaluate Music Therapy on Irritability and Impulsivity in Patients With Huntington's Disease (MUSIC-HD)
Pilot Study Evaluating the Benefits of Music Therapy Combined With Conventional Treatment on Irritability and Impulsivity in Patients With Huntington's Disease (MUSIC-HD)
Poitiers University Hospital
15 participants
Oct 15, 2024
INTERVENTIONAL
Conditions
Summary
The study is an open-label clinical trial evaluating whether music therapy combined with conventional management reduces irritability and impulsivity in 15 patients with early-stage Huntington's disease. This pilot study aims to show the interest of alternative non-pharmacological measures such as a digital music therapy tool, adapted to an audience of Huntington's patients, to help manage the psychobehavioral symptoms frequently observed in this affection, and to avoid breakdowns due to caregiver exhaustion.
Eligibility
Inclusion Criteria8
- Age >= 18 years
- Huntington disease genetically confirmed by the presence of at least 35 repeats of the CAG triplet in exon 1 of the HTT gene
- UHDRS (Unified Huntington's disease Rating Scale) score <= 5 with a diagnostic confidence score =4
- Absence of significant cognitive impairment MoCA >=24
- Stable drug therapy in the 28 days prior inclusion and during the study
- Without legal tutors or subordination
- Affiliated to a health insurance system as required by the French law on biomedical research
- Written informed consent for participation in the study
Exclusion Criteria4
- Inability to give free and informed consent for study participation
- Significant hearing impairment
- Participating to another study the day of enrollement
- Persons benefiting from enhanced protection, i.e.persons deprived of their liberty by a judicial or administrative decision, adults under legal and finally patients in a vital emergency situation.
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Interventions
Music therapy carried out with Music Care
Locations(1)
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NCT06414967