Sleep Apnea and Cognition in Older Adults
Cross-sectional Investigation of Sleep Apnea and Cognition in Older Adults Using the ANNE Vital Sign System
Sunnybrook Health Sciences Centre
300 participants
Apr 9, 2024
OBSERVATIONAL
Conditions
Summary
The goal of this cross-sectional, observational, medical device trial is to examine the association of several sleep parameters, including specific respiratory events and an apnea-hypopnea index, with cognitive performance in older adults. The main question the study aims to answer is: Is there an association between sleep parameters with cognitive performance? Researchers will collect sleep parameters from participants using a device called the ANNE Vital Sign System and will test whether they are associated with performance on different memory and thinking tasks. Participants will: Complete a battery of cognitive tests to assess their memory and thinking performance. Wear the ANNE Vital Sign System continuously for a period of 24 hours.
Eligibility
Inclusion Criteria8
- Sufficient knowledge of English to understand and provide informed consent
- Competent to provide consent
- Aged 55-85, Male and Female
- ≥ 8 years of education
- Capable of cooperating for the duration of the study procedures and assessments
- No frank cognitive impairment or dementia
- Sufficient (corrected) vision to participate in cognitive testing
- Sufficient (corrected) hearing to participate in cognitive testing
Exclusion Criteria16
- Cannot read and comprehend English language instructions
- Major cardio- or cerebro-vascular event (heart attack, stroke, significant white matter changes)
- Unstable diseases (e.g., pulmonary, endocrine disorder)
- Active malignancy or infectious diseases
- History of significant learning disability
- Major psychiatric/neurologic/degenerative disorder, including a diagnosis of mild cognitive impairment or dementia
- History of significant head trauma or recurrent concussions requiring hospitalization followed by persistent neurologic defaults or known structural brain abnormalities
- Pain or sleep disorder that could interfere with cognitive testing
- Major medical concerns that might interfere with cognitive testing
- Recent history of substance/drug abuse
- Known nickel allergy
- Known cardiac implantable device
- Known arrhythmias
- Outside the included age range
- Pregnant or breast feeding
- Otherwise unable to use the ANNE sensors; for example, finger amputations.
Interested in this trial?
Get notified about updates and connect with the research team.
Interventions
The ANNE Vital Sign System is a pair of non-invasive, flexible sensors originally designed for vital signs monitoring in the paediatric intensive care unit.
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT06423118