RecruitingNot ApplicableNCT06423651

Benefits of Combining MCT With CR in the Recovery of Patients With Psychotic Spectrum Disorders

Benefits of Combining Metacognitive Training (MCT) With Cognitive Remediation (CR) in the Recovery of Patients With Psychotic Spectrum Disorders (CR+MCTp)

Sponsor

Universitat Autonoma de Barcelona

Enrollment

160 participants

Start Date

Sep 1, 2022

Study Type

INTERVENTIONAL

Conditions

Schizophrenia Schizoaffective Disorder Delusional Disorder Schizophrenia Spectrum and Other Psychotic Disorders Schizophreniform Disorders Brief Psychotic Disorder

Summary

The goal of this clinical trial is to compare the efficacy of combined REHACOP + MCT alone in persons with nonaffective psychotic disorder in terms of recovery. The main questions it aims to answer are: * Does combined REHACOP + MCT therapy increase the clinical recovery in persons with nonaffective psychotic disorder (compared to MCT alone)? * What is the impact of combined REHACOP + MCT therapy compared to MCT therapy alone on personal/psychological recovery, cognitive biases, and social cognition, taking gender differences into account? * What is the durability of the effects of combined REHACOP + MCT therapy compared to MCT therapy alone on clinical recovery, personal recovery, cognitive biases, and social cognition in the long term? Researchers will compare REHACOP+MCT therapy to MCT alone to see if there are differences in personal/psychological recovery. Participants will: * Participate in Metacognitive Training or in combined REHACOP + Metacognitive training therapy. * Do 8 weekly sessions of 45-60 minutes (MCT group). * Do 12 weekly sessions of 45-60 minutes (RECHACOP+MCT group). * Visit the clinic for checkups and tests. * Answer self-administered tests.

Eligibility

Min Age: 16 YearsMax Age: 55 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether combining two types of therapy — metacognitive training (learning to think differently about thoughts) and cognitive rehabilitation (brain exercises) — helps people with psychotic disorders like schizophrenia recover thinking skills and mental functioning. **You may be eligible if...** - You have been diagnosed with schizophrenia, schizoaffective disorder, delusional disorder, or a related psychotic condition - You are in a stable phase of your illness (no hospitalization in the past 3 months) - You are consistently taking your prescribed medications - You show cognitive difficulties on standard thinking tests **You may NOT be eligible if...** - You have a brain injury, dementia, or intellectual disability (IQ below 70) - You have high levels of hostility or suspiciousness on a clinical scale - You have a severe substance use disorder - You have already participated in metacognitive training or cognitive rehabilitation in the past year Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALCognitive Remediation (REHACOP)

REHACOP is a structured neuropsychological rehabilitation program that covers most of the cognitive deficits present in psychotic disorder: attention, learning and memory, executive functions, language, social cognition, daily life activities, social skills and psychoeducation. The modules of language, social cognition and psychoeducation will not be used in the present clinical trial. Each module includes a hierarchy of exercises based on the cognitive subarea to be worked on and the grade of difficulty demanded for the performance of each task.The format of the sessions will be the same as MCT, that is, groups of 6-10 patients who will receive weekly sessions of 45-60 minutes in length. In this case, the duration of the intervention will be 12 sessions.

BEHAVIORALMetacognitive Training (MCT)

The MCT consists in 8 weekly sessions of 45-60 minutes in length. Each group of patients should be made up of 6-10 patients. The material of the training program is available online at: http://www.uke.de/mkt. The material contains 16 powerpoint presentations (2 per each module), one manual and 6 pamphlets of tasks to do at home. The modules are as follows: Module 1: Attribution; Module 2: Jumping to conclusions (1st part); Module 3: Changing beliefs; Module 4: To emphatise (1st part); Module 5: Memory; Module 6: To emphatise (2nd part); Module 7: Jumping to conclusions (2nd part); and Module 8: Self-esteem and mood.