Clinical Outcome in Patients With INPH
Phenotypes, Biomarkers and Pathophysiology in INPH
Xuanwu Hospital, Beijing
200 participants
May 15, 2024
OBSERVATIONAL
Conditions
Summary
The aim of this study is to determine the clinical spectrum and natural progression of idiopathic normal pressure hydrocephalus （iNPH ) and related disorders in a prospective single center study, identify digital, imaging and molecular biomarkers that can assist in diagnosis and therapy development and study the etiology and molecular mechanisms of these diseases.
Eligibility
Inclusion Criteria1
- patients who was diagnosed as idiopathic normal pressure hydrocephalus
Exclusion Criteria1
- patient received surgical treatment or interventional treatment before patient is pregnant patient unable to complete follow-up patient with other types of hydrocephalus other nervous system diseases
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Interventions
Diagnostic Test: high throughput sequencing and electromyography Whole Genome Sequencing, Whole Exome Sequencing, Transcriptomics, Proteomics, Metabolomics and imaging, such as DTIALPS
Whole Genome Sequencing, Whole Exome Sequencing, Transcriptomics, Proteomics, Metabolomics and imaging, such as DTIALPS
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT06428734