RecruitingNCT06486909

Shunt-dependency After aSAH - Role of Early Hyperglycaemia in CSF and Blood

Shunt-dependency After Aneurysmal Subarachnoid Haemorrhage - the Role of Early Hyperglycaemia in Cerebro-spinal Fluid and Blood


Sponsor

Isabel Hostettler

Enrollment

160 participants

Start Date

Mar 26, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

The goal of this study is to confirm the association of early increased glucose levels in cerebro-spinal fluid (CSF) and ventriculo-peritoneal-shunt (VPS)-dependency also evaluating the influence of blood glucose on VPS dependency in patients suffering from an aneurysmal subarachnoid haemorrhage (aSAH). The main questions we aim to answer are: * Is there an association of glucose levels on VPS dependency in patients requiring extra-ventricular-drain (EVD) placement for aSAH? * In addition, if there is, what is the influence the course of glucose levels has on VPS dependency? Glucose levels in CSF and serum will be measured on admission, or in case of CSF, upon EVD placement. Glucose in CSF will then be measured every day until EVD removal together with serum glucose. Follow-up will be conducted in person after 3 and 6 months.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying Blood Serum Sample and Cerebrospinal Fluid (CSF) Sample for people with aneurysm, ruptured, hydrocephalus, and other related conditions. The study is currently recruiting participants at 3 locations.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIAGNOSTIC_TESTCerebrospinal Fluid (CSF) Sample

Samples for glucose in CSF will be taken upon EVD/LD placement until EVD/LD removal (within the first 14 days).

DIAGNOSTIC_TESTBlood Serum Sample

Samples for glucose in blood serum will be completed every day, for the first 14 days.


Locations(3)

Cantonal Hospital Aarau

Aarau, Switzerland

University Hospital Basel

Basel, Switzerland

Cantonal Hospital St Gallen

Sankt Gallen, Switzerland

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NCT06486909


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