RecruitingNot ApplicableNCT06430931

Biological OviTex Versus Synthetic Graft in Robotic Prolapse Surgery

Biological OviTex Versus Synthetic Graft in Robotic Prolapse Surgery: a Multicentre, Phase 11-111, Partially Randomised Patient Preference Trial


Sponsor

Meander Medical Center

Enrollment

184 participants

Start Date

Dec 6, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

This prospective study aims to assess the efficacy of the OviTex 1S permanent mesh in pelvic floor surgery in comparison with the current standard polypropylene mesh.


Eligibility

Min Age: 18 Years

Inclusion Criteria5

  • Indication for VMR or SCR set by the treating surgeon/gynecologist in accordance to the current guidelines on rectal and pelvic prolapse;
  • Counselled for therapeutic options and given informed consent for VMR or SCR;
  • Counselled for different types of mesh (OviTex or Prolene) and randomisation;
  • Written informed consent for randomisation, OviTex implant or Prolene;
  • Written informed consent for observational data collection.

Exclusion Criteria6

  • Mentally incompetent patients (unable to fulfil questionnaires).
  • Allergy to ovine rumen.
  • A medical history of pelvic radiation therapy.
  • Scheduled for a redo-rectopexy.
  • A medical history of previously implanted pelvic floor meshes or native tissue.
  • Language barrier

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Interventions

PROCEDUREMinimal invasive abdominal prolapse surgery using Polypropylene mesh

All procedures will be performed with robotic assistance of the da Vinci Si-HD (intuitive Surgical, Inc, Sunnyvale, CA).

PROCEDUREMinimal invasive abdominal prolapse surgery using OviTex 1S permanent mesh

All procedures will be performed with robotic assistance of the da Vinci Si-HD (intuitive Surgical, Inc, Sunnyvale, CA).


Locations(1)

Meander Medisch Centrum

Amersfoort, Utrecht, Netherlands

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NCT06430931


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