Prolapse Clinical Trials

98 recruitingLast updated: July 25, 2026

There are 98 actively recruiting prolapse clinical trials across 32 countries. Studies span Not Applicable, Phase 3, Phase 2, Phase 4. Top locations include Durham, North Carolina, United States, Istanbul, Turkey (Türkiye), Cleveland, Ohio, United States. Updated daily from ClinicalTrials.gov.


Prolapse Trials at a Glance

98 actively recruiting trials for prolapse are listed on ClinicalTrialsFinder across 6 cities in 32 countries. The largest study group is Not Applicable with 55 trials, with the heaviest enrollment activity in Durham, Istanbul, and Cleveland. Lead sponsors running prolapse studies include Gaziosmanpasa Research and Education Hospital, Assiut University, and Centre Hospitalier Universitaire, Amiens.

Browse prolapse trials by phase

Treatments under study

About Prolapse Clinical Trials

Looking for clinical trials for Prolapse? There are currently 3 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Prolapse trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Prolapse clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 98 trials

Recruiting

Ethicon Pelvic Mesh Post Market Clinical Follow-up Registry

pelvic organ prolapseStress Urinary Incontinence
Ethicon, Inc.1,000 enrolled10 locationsNCT04829175
Recruiting

GYNEMESH PS Mesh Post Marketing Clinical Follow-Up Study

pelvic organ prolapse
Ethicon, Inc.100 enrolled3 locationsNCT04829058
Recruiting
Not Applicable

The AMPER Study: Evaluation of the Efficacy of Human Amniotic Membrane Grafting in Preventing Mesh Exposure in Vaginal Reconstructive Surgery Using Polypropylene Mesh.

Pelvic Organ Prolapse Vaginal SurgeryStress Urinary Incontinence in Women
Hospital General de Agudos J. M. Penna330 enrolled1 locationNCT07414849
Recruiting

Centered Surgery - Preoperative Counseling and Patient Satisfaction

pelvic organ prolapse
The Cleveland Clinic106 enrolled1 locationNCT07471464
Recruiting
Not Applicable

Combined Effects of Pelvic Floor Retraining and Hypopressive Exercises in Uterine Prolapse Outcomes

Uterine Prolapse
Riphah International University32 enrolled1 locationNCT07642180
Recruiting
Not Applicable

Vaginal Vault Native Tissue Suspension

pelvic organ prolapse
Assiut University10 enrolled1 locationNCT07517965
Recruiting
Not Applicable

Evaluation of a Personalizable Pessary for Pelvic Organ Prolapse

Pelvic organ prolapse (POP)
University of Alberta43 enrolled1 locationNCT06954701
Recruiting

Performance of SYMMCORA® vs. V-Loc® Suture Material in Patients Undergoing Laparoscopic Total Hysterectomy

Ovarian CancerCervical CancerEndometrial Cancer+5 more
Aesculap AG132 enrolled2 locationsNCT06024109
Recruiting
Not Applicable

BELIEVE Trial: Bulking vErsus sLing for Treating Stress Urinary IncontinEnce at the Time of Vaginal prolapsE Repair (BELIEVE)

Stress Urinary IncontinenceVaginal prolapse
University Hospitals Cleveland Medical Center476 enrolled1 locationNCT06754046
Recruiting
Not Applicable

Evaluation of SINGLE PORT (SP) Robotic Technology in Colorectal Surgery

Colo-rectal CancerRectal ProlapseColostomy Stoma+1 more
University of California, Davis25 enrolled1 locationNCT05321134
Recruiting
Not Applicable

The RECOVER Study - Postpartum Recovery of Pelvic Floor Structures and the Impact of Early Rehabilitation

Pelvic organ prolapse (POP)Urinary IncontinencePelvic Floor Muscle Training+5 more
Vastra Gotaland Region380 enrolled2 locationsNCT07430865
Recruiting
Not Applicable

LAparoscopic Preventive PRErectal Mesh

Urogenital Prolapse
University Hospital, Lille834 enrolled9 locationsNCT03766048
Recruiting
Not Applicable

Comparison of the Effectiveness and Learning Curve of Laparoscopic Pectopexy Versus Laparoscopic Sacrocolpopexy

Apical Prolapse
Ain Shams University30 enrolled1 locationNCT07596498
Recruiting
Not Applicable

Prophylactic Laparoscopic Suspension After McCall

Prolapse Pelvic
Insel Gruppe AG, University Hospital Bern114 enrolled1 locationNCT04560543
Recruiting

Development and Validation of a Risk Prediction Model for De Novo Stress Urinary Incontinence After Pelvic Floor Reconstruction Surgery

Pelvic organ prolapse (POP)Stress Urinary Incontinence (SUI)
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine382 enrolled1 locationNCT07601282
Recruiting
Not Applicable

Early Mitral ValvE Repair Versus Watchful Waiting for Asymptomatic SEvere Degenerative Mitral Regurgitation

Degenerative Mitral Regurgitation (MR) Due to Leaflet Prolapse
Centre Hospitalier Universitaire, Amiens424 enrolled2 locationsNCT03389542
Recruiting
Not Applicable

The Finnish Uterine Prolapse Surgery Trial (The Fin-UP Trial)

Pelvic organ prolapse (POP)Uterine ProlapsePelvic Organ Prolapse Vaginal Surgery
Tampere University Hospital426 enrolled6 locationsNCT07566949
Recruiting
Not Applicable

Arrhythmic Mitral Valve Prolapse Detection Using Long-term Ambulatory Rhythm Monitoring

Mitral valve prolapseVentricular Arrythmia
Universitaire Ziekenhuizen KU Leuven60 enrolled1 locationNCT06378996
Recruiting
Not Applicable

Accelerometer Measured Early Recovery After Prolapse Surgery

pelvic organ prolapsePelvic organ prolapse (POP)Pelvic Organ Prolapse Vaginal Surgery+1 more
NICHD Pelvic Floor Disorders Network288 enrolled7 locationsNCT07218016
Recruiting
Not Applicable

Poly-L-Lactic Acid for Vulvovaginal Tissue Regeneration

Pelvic organ prolapse (POP)Pelvic Floor DisorderCystocele
Cassandra Kisby20 enrolled1 locationNCT07544667