RecruitingNCT06443333

National, Multicentric Registry Study on Neuroimmunological Diseases in China

Sponsor

Xuanwu Hospital, Beijing

Enrollment

7,000 participants

Start Date

Dec 1, 2020

Study Type

OBSERVATIONAL

Conditions

Myasthenia Gravis Autoimmune Encephalitis Multiple Sclerosis Acute Disseminated Encephalomyelitis NMO Spectrum Disorder Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease

Summary

The aim of this study is to establish a real-world clinical neuroimmune disease research cohort, to follow up and observe the prognosis of patients with different subtypes and subgroups, and to provide support for the treatment, early warning, and outcome prediction research of neuroimmune diseases.

Eligibility

Plain Language Summary

Simplified for easier understanding

This study builds a national registry of people in China diagnosed with neuroimmunological diseases — conditions where the immune system mistakenly attacks the brain, spinal cord, or nerves — including multiple sclerosis (MS), neuromyelitis optica spectrum disorder (NMOSD), and related conditions. The goal is to better understand how these diseases progress and respond to treatment in the Chinese population. **You may be eligible if...** - You have been diagnosed at Xuanwu Hospital (Capital Medical University) with MS, NMOSD, or a related neuroimmune condition - Your diagnosis meets established international criteria - You consent to having your medical data included in the registry **You may NOT be eligible if...** - You do not have a confirmed neuroimmunological diagnosis - Your diagnosis was made at a different institution not participating in the study - You do not consent to data collection Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERData collection and follow-up observation

At the time of enrollment, the patient's biological samples are collected to obtain genetic information. Following enrollment, trained investigators carry out a 2-year follow-up observation through face-to-face, telephone call or online visits. During the follow-up, basic clinical information, laboratory tests, imaging examinations, neurophysiology, clinical classification, medication use, and scale assessments are collected.

OTHERData collection

Collect demographic and genetic information from healthy volunteers upon enrollment.

Locations(1)

Xuanwu Hospital ,Capital Medical University

Beijing, Beijing Municipality, China

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NCT06443333

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