RecruitingPhase 2NCT06446479

Effects of THC on Alcohol Consumption and Neural Correlates of Reward


Sponsor

University of Colorado, Denver

Enrollment

28 participants

Start Date

Jul 1, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

Alcohol and cannabis are often used together such that their effects overlap, but little is known about the neural mechanisms that underlie simultaneous use. High doses of THC have not been well-studied in the laboratory, and it is unclear how high doses of THC may impact alcohol consumption patterns. The proposed study will explore the effects of oral THC (20mg dronabinol) vs. placebo on neural reward, alcohol self-administration and naturalistic co-use patterns.


Eligibility

Min Age: 21 YearsMax Age: 40 Years

Inclusion Criteria3

  • Drink alcohol
  • Use cannabis
  • Contact site for additional details

Exclusion Criteria2

  • MRI contraindications (implanted metal, weight > 315 lb, etc.).
  • Contact site for additional details

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Interventions

DRUGDronabinol Pill

Dronabinol 20 mg

DRUGPlacebo

placebo


Locations(1)

University of Colorado Anschutz Medical Campus

Aurora, Colorado, United States

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NCT06446479


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