Cannabis Use Disorder Clinical Trials

37 recruiting

Cannabis Use Disorder Trials at a Glance

36 actively recruiting trials for cannabis use disorder are listed on ClinicalTrialsFinder across 6 cities in 6 countries. The largest study group is Not Applicable with 17 trials, with the heaviest enrollment activity in Charleston, Boston, and Aurora. Lead sponsors running cannabis use disorder studies include Medical University of South Carolina, Yale University, and Massachusetts General Hospital.

Browse cannabis use disorder trials by phase

Treatments under study

About Cannabis Use Disorder Clinical Trials

Looking for clinical trials for Cannabis Use Disorder? There are currently 37 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Cannabis Use Disorder trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Cannabis Use Disorder clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 36 trials

Recruiting
Phase 2

A Study of Cannabidiol in Young Adult Cannabis Users

Cannabis Use Disorder
University of Colorado, Denver200 enrolled1 locationNCT06569394
Recruiting
Phase 2

Cannabidiol and Cannabis Concentrate Users

Cannabis Use Disorder
University of Colorado, Denver120 enrolled1 locationNCT06575751
Recruiting
Not Applicable

Stress and Pain in People Living With HIV

PainDepressionStress+2 more
Yale University120 enrolled1 locationNCT06784908
Recruiting
Not Applicable

RS-tDCS for Cannabis Use Disorder: The C.A.R.E.S. Initiative

Cannabis Use Disorder
NYU Langone Health46 enrolled1 locationNCT07184983
Recruiting
Not Applicable

A Brief Intervention for Cannabis Use

Cannabis Use Disorder
Medical University of South Carolina62 enrolled1 locationNCT06395389
Recruiting
Phase 3

Cannabis-Tobacco Co-Use Treatment Study

Tobacco Use DisorderTobacco Use CessationCannabis Use+2 more
Medical University of South Carolina200 enrolled1 locationNCT06883162
Recruiting
Not Applicable

Effects of Action-Based Cognitive Remediation on Substance Misuse in Early Phase Psychosis

Alcohol Use DisorderPsychosisCannabis Use Disorder
Nova Scotia Health Authority50 enrolled2 locationsNCT07056894
Recruiting
Not Applicable

Determining the Effect of Six Weeks of Cannabis Abstinence on Fronto- Striatal fMRI Markers in Adolescents With Cannabis Use Disorder (ABSCAN)

Cannabis Use Disorder
University of Minnesota64 enrolled1 locationNCT06124846
Recruiting
Not Applicable

Neuroimaging of Adolescent Cannabis Use Treatment

Cannabis UseCannabis SmokingCannabis Use Disorder+3 more
Indiana University80 enrolled1 locationNCT07340554
Recruiting
Not Applicable

Repetitive Transcranial Magnetic Stimulation for Cannabis Use Disorder

Cannabis Use Disorder
Centre for Addiction and Mental Health46 enrolled1 locationNCT05859347
Recruiting
Not Applicable

Phenotyping Patients With Alcohol and Cannabis Use Disorders Using the Addictions Neuroclinical Assessment

Alcohol Use DisorderCannabis Use Disorder
Centre for Addiction and Mental Health400 enrolled1 locationNCT05855668
Recruiting
Phase 1

Psilocybin-assisted Treatment for Cannabis Use Disorder

Cannabis Use Disorder
Johns Hopkins University12 enrolled1 locationNCT06660381
Recruiting
Not Applicable

Cannabis Reduction and Functional Outcomes

Cannabis Use Disorder
Medical University of South Carolina176 enrolled1 locationNCT07218471
Recruiting

Study of Oral Fluid Testing Approach

Cannabis UseCannabis Use DisorderCannabis Intoxication
Boston Children's Hospital200 enrolled1 locationNCT06891235
Recruiting
Early Phase 1

SV2A Density Cannabis Use Disorder

HealthyCannabis Use Disorder
Yale University51 enrolled1 locationNCT05472818
Recruiting
Not Applicable

Integrated Treatment for Enhancing Growth in Recovery During Adolescence

Alcohol Use DisorderCannabis Use Disorder
Massachusetts General Hospital294 enrolled2 locationsNCT06395467
Recruiting
Not Applicable

Preliminary Efficacy Trial of a Digital Intervention for Depression and Cannabis Use

Depression - Major Depressive DisorderMental DisorderCannabis Use Disorder
Massachusetts General Hospital80 enrolled1 locationNCT06878859
Recruiting

SV2 PET Imaging With [11C]APP311

HealthyCannabis Use DisorderSchizophrenia and Other Psychotic Disorders
Yale University250 enrolled1 locationNCT03995121
Recruiting
Phase 4

Evaluation of Suvorexant for Reduction of Brain Reactivity in Patients With Cannabis Use Disorder (Pilot Study)

Cannabis Use DisorderCue-reactivityFunctional MRI+1 more
Massachusetts General Hospital20 enrolled1 locationNCT06584942
Recruiting
Phase 1Phase 2

Mitigating PTSD-CUD After Sexual Assault

Cannabis Use DisorderPosttraumatic Stress Disorder
University of Nevada, Las Vegas68 enrolled6 locationsNCT05989841