Effectiveness of Glycyrrhizin as Intracanal Medication in Root Canal Disinfection and Inflammatory Cytokines
Clinical Investigation of the Effectiveness of Glycyrrhizin as Intracanal Medication in Root Canal Disinfection and Inflammatory Cytokines
Mansoura University
36 participants
Mar 20, 2022
INTERVENTIONAL
Conditions
Summary
The objective of this study is to investigate "clinically" the effectiveness of Glycyrrhizin based intracanal medication compared to the commonly used intracanal medicaments (calcium hydroxide Ca(OH)2 and Ledermix) on the levels of bacteria and inflammatory cytokines in root canals and periradicular tissues of teeth with apical periodontitis.
Eligibility
Inclusion Criteria1
- Single-rooted with pulp necrosis and apical periodontitis.
Exclusion Criteria4
- Receiving antibiotic treatment within the preceding 3 months.
- Reporting systemic disease.
- Teeth that could not be isolated with rubber dam.
- Teeth with periodontal pockets deeper than 3 mm.
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Interventions
Intracanal medication
Intracanal medication
Intracanal medication
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06453304