RecruitingPhase 2Phase 3NCT06566508
Effectiveness of Asiaticoside as Intracanal Medication on Infectious/Inflammatory Contents in Teeth With Apical Periodontitis
Sponsor
Mansoura University
Enrollment
36 participants
Start Date
Nov 20, 2023
Study Type
INTERVENTIONAL
Conditions
Summary
The objective of this study is to investigate \"clinically\" the effectiveness of Asiaticoside based intracanal medication compared to the commonly used intracanal medicaments (calcium hydroxide Ca(OH)2 and Ledermix) on the levels of bacteria and inflammatory cytokines in root canals and periradicular tissues of teeth with apical periodontitis.
Eligibility
Min Age: 20 YearsMax Age: 60 Years
Inclusion Criteria1
- • Single-rooted with pulp necrosis and apical periodontitis.
Exclusion Criteria4
- Receiving antibiotic treatment within the preceding 3 months.
- Reporting systemic disease.
- Teeth that could not be isolated with rubber dam.
- Teeth with periodontal pockets deeper than 3 mm.
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Interventions
DRUGCalcium Hydroxide Intracanal medication
Calcium Hydroxide Intracanal medication
DRUGLeddermix Intracanal medication
Leddermix Intracanal medication
DRUGAsiaticoside Intracanal medication
Asiaticoside Intracanal medication
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT06566508