RecruitingNCT06459024

Master Framework For Relapse or Refractory Acute Myeloid Leukemia

Master Framework For Relapse or Refractory Acute Myeloid Leukemia- IMPACT STREAM - A Prospective Observational Study of Treatment Outcomes


Sponsor

Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS

Enrollment

4,000 participants

Start Date

Jun 28, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

This is an observational (non-interventional), prospective, cohort study that will collects data from patients diagnosed with relapsed or refractory acute myeloid leukemia afferent to the participanting clinical sites


Eligibility

Min Age: 6 Years

Inclusion Criteria3

  • Patients with AML diagnosis according to WHO2022 or ICC2022
  • Treatment failure (i.e. relapse, refractory or progression, including MRD) according to ELN2022 criteria
  • Participant or his/her legal representative is willing and able to give informed consent for participation in the study

Exclusion Criteria1

  • Patients included in clinical trials may be enrolled except where otherwise specified in the experimental protocol.

Interventions

OTHERRegistration into the STREAM platform

All patients fulfilling eligibility criteria will be registered into the STREAM platform. Baseline and follow up information will be recorded for each patient enrolled. Each patient will be followed up according to normal clinical practice up to 4 years.


Locations(38)

Ospedale Sant'Andrea

Roma, RM, Italy

University Hospital Aachen

Aachen, Germany

University Hospital Greifswald

Greifswald, Germany

University Hospital Halle

Halle, Germany

University Hospital of Rostock

Rostock, Germany

Policlinico Sant'Orsola-Malpighi

Bologna, BO, Italy

Ospedale "A. Perrino"

Brindisi, BR, Italy

ASST Spedali Civili

Brescia, BS, Italy

Azienda Ospedaliera S. Croce e Carle

Cuneo, CN, Italy

Ospedale Valduce

Como, CO, Italy

ASST Cremona

Cremona, CR, Italy

AOU Universitaria Arcispedale Sant'Anna

Ferrara, FE, Italy

IRCCS Ospedale Policlinico San Martino

Genova, GE, Italy

Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico

Milan, MI, Italy

ASST Grande Ospedale Metropolitano Niguarda

Milan, MI, Italy

Azienda Ospedaliera Ospedali Riuniti Villa Sofia - Cervello

Palermo, PA, Italy

Presidio Ospedaliero "Santo Spirito"

Pescara, PE, Italy

Ospedale Santa Maria della Misericordia

Perugia, PG, Italy

Ospedale Santa Maria delle Croci

Ravenna, RA, Italy

Fondazione Policlinico Tor Vergata

Roma, RM, Italy

Policlinico Umberto I

Roma, RM, Italy

Policlinico Universitario Fondazione Agostino Gemelli

Roma, RM, Italy

Ospedale infermi di Rimini

Rimini, RN, Italy

AOU San Giovanni di Dio e Ruggi d'Aragona

Salerno, SA, Italy

AOU Città della Salute e della Scienza di Torino

Torino, TO, Italy

AO Ordine Mauriziano

Torino, TO, Italy

IOV Istituto Oncologico Veneto

Castelfranco Veneto, TV, Italy

ASST Valle Olona

Busto Arsizio, VA, Italy

AOU Careggi

Florence, Italy

IRST Istituto Romagnolo per lo Studio dei Tumori Dino Amadori

Meldola, Italy

Azienda Ospedaliera di Rilievo Nazionale Antonio Cardarelli

Napoli, Italy

AOU Maggiore della Carità

Novara, Italy

Azienda Ospedale-Università Padova

Padua, Italy

Ospedale San Bortolo

Vicenza, Italy

The Hospital of Lithuanian University of Health Sciences Kauno Klinikos

Kaunas, Lithuania

University Clinical Center in Gdańsk

Gdansk, Poland

Fundeni Clinical Institute

Bucharest, Romania

University Hospital La Fe

Valencia, Spain

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