Tenapanor in Synucleinopathy-Related Constipation

This study investigates whether tenapanor, a medication currently used for irritable bowel syndrome, can help relieve constipation in people with synucleinopathy-related conditions — such as Parkinson's disease or Lewy body dementia — where constipation is a common and distressing symptom. **You may be eligible if...** - You have a synucleinopathy such as Parkinson's disease or Lewy body disease - You experience constipation related to your condition - Your doctor determines you meet the study's medical requirements **You may NOT be eligible if...** - The specific exclusion criteria have not been published for this trial at this time - You should confirm eligibility details directly with your care team Talk to your doctor to see if this trial is right for you.