RecruitingNot ApplicableNCT06462170

Pancreatic Insulin Production Capacity (PIPC) - a Feasibility Study

The Feasibility of an Innovative Protocol to Demonstrate the Impact of Positive Energy Balance on Pancreatic Insulin Production Capacity (PIPC)

Sponsor

Ottawa Hospital Research Institute

Enrollment

90 participants

Start Date

Jun 24, 2024

Study Type

INTERVENTIONAL

Conditions

Type 2 Diabetes

Summary

The standard treatment for Type 2 diabetes involves management of the disease based on average of blood glucose control over the past few months. In this study, the investigators test for the participants' ability to produce insulin, which is the hormone that the body makes to control blood sugar levels. The body produces insulin in response to eating. The participants will drink a meal replacement shake, and then test the blood for levels of insulin produced over 2 hours. With blood tests taken five times over two hours, the investigators will measure the blood glucose (sugar), and insulin levels. This study will assess the differences in insulin produced in the participants and try to understand the reasons for these differences.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This small feasibility study measures the pancreas's remaining ability to produce insulin in people with Type 2 diabetes who are not yet on insulin therapy, to better understand what's happening in early-to-mid stage Type 2 diabetes. **You may be eligible if...** - You are 18 or older - You have been diagnosed with Type 2 diabetes - You are NOT currently using insulin injections **You may NOT be eligible if...** - You have been diagnosed with a different type of diabetes (e.g., Type 1, MODY) - You are allergic to any ingredients in Boost meal replacement shakes (used during the test) - You are unable to fast from midnight and attend in person for the morning testing protocol Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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