RecruitingNCT06463756

AI Models to Predict Thyroid Cartilage Invasion in Laryngeal Carcinoma

CT-based Radiomics, Two-dimensional and Three-dimensional Deep Learning Models to Predict Thyroid Cartilage Invasion in Laryngeal Carcinoma: a Multicenter Study


Sponsor

First Affiliated Hospital of Chongqing Medical University

Enrollment

400 participants

Start Date

Aug 13, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

This retrospective study was to develop and verify CT-based AI model to preoperatively predict the thyroid cartilage invasion of laryngeal cancer patients, so as to provide more accurate diagnosis and treatment basis for clinicians. In addition, the researchers investigated the prediction of survival outcomes of patients by the above optimal models.


Eligibility

Min Age: 18 YearsMax Age: 81 Years

Inclusion Criteria3

  • Availability of complete clinical data
  • Surgery-proven or biopsy-proven diagnosis of laryngeal squamous cell carcinoma
  • CT examination performed within 2 weeks before surgery

Exclusion Criteria3

  • Patients who received preoperative chemotherapy or radiation therapy
  • CT images with significant artifacts
  • Patients with tumor recurrence

Interventions

OTHERAI

Radiomics extracts quantitative information from medical images to generate high-dimensional feature vectors for analysis. It aims to provide insights into disease processes and improve diagnosis. Deep learning utilizes neural networks with multiple layers to learn complex patterns from data. In medical imaging, it enables accurate and efficient analysis for disease detection and diagnosis.


Locations(1)

The First Affiliated Hospital of Chongqing Medical University

Chongqing, China

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NCT06463756


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