RecruitingNCT06466811

Prediction of Undesired Obstruction in External Ventricular Drains.

Identification of Patients at Risk of Undesired Obstruction in External Ventricular Drain: Development of a Score Based on the Extent of Intra-ventricular Hemorrhage. A Single-Center, Prospective Observational Study.

Sponsor

Nantes University Hospital

Enrollment

640 participants

Start Date

Jul 4, 2024

Study Type

OBSERVATIONAL

Conditions

Intensive Care Unit

Summary

Acute obstructive hydrocephalus often complicates intraventricular hemorrhage (IVH). The insertion of an external ventricular drain (EVD) is typically necessary in order to alleviate intracranial pressure by draining excess fluid. However, dysfunction of the EVD whether due to malposition or obstruction, can exacerbate hydrocephalus in an already compromised brain. EVD dysfunction must therefore be promptly detected and treated. Consequently, identifying high-risk patients and closely monitoring them is imperative. While IVH is known to increase the risk of obstruction in the natural cerebrospinal fluid outflow tract, its association with ventricular drain obstruction remains unproven.

Eligibility

Min Age: 18 Years

Inclusion Criteria4

Patient older than 18 years old,
admitted to the ICU,
with first EVD inserted for less than 12 hours,
and brain imaging (CT or MRI) available in the timespan "24 hours before to 24 hours after" the EVD insertion.

Exclusion Criteria6

EVD intentionally occluded immediately after its insertion,
purulent cerebrospinal fluid
Pregnant or breast-feeding patient
Moribund patient or patient with decision of withholding or withdrawing life-sustaining treatment within the 12 hours
Patient with no health insurance
Patient under guardianship