RecruitingNCT06469515

Older People's Neurocognitive Recovery After Cardiac Surgery

Enhanced Continuity of Postoperative Care for Older People in Their Neurocognitive Recovery After Cardiac Surgery


Sponsor

Karolinska Institutet

Enrollment

220 participants

Start Date

Nov 1, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

Society is aging and advantages in anesthesia and surgery allow more complex interventions in older persons. Old age is a significant risk factor for the development of postoperative neurocognitive decline characterized by a gradual decrease in performance in several cognitive domains such as memory, attention, information processing, and executive functions, leading to problems with performing daily activities and maintaining independence and postoperative complications. The purpose of this study is to measure older persons' postoperative neurocognitive function, to detect neurocognitive decline, and to identify risk factors and difficulties in daily living as well as explore close relatives' experiences of it. We will include 220 participants ≥65 years of age undergoing planned cardiac surgery. Cognitive symptoms and signs and neurocognitive function will be assessed up to 6 months after surgery. Risk/affected factors such as delirium, functional status, recovery, depression, and healthcare-related quality of life, as well as close relative's experiences and burden, will be measured. The results will have immediate relevance for a substantial number of older persons undergoing surgery, and their close relatives, by enhancing knowledge about postoperative cognitive decline and recovery, and subsequently identifying what support needs to be implemented.


Eligibility

Min Age: 65 Years

Inclusion Criteria3

  • Scheduled for elective or urgent open-heart surgery or minimally invasive cardiac surgery
  • Resident in the area/region for the current thoracic clinic
  • Able to read and understand Swedish

Exclusion Criteria2

  • Physical, mental, and cognitive difficulties that prevent the individual from completing the cognitive tests
  • Undergone surgery within the last 6 months

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Interventions

OTHERElective or urgent cardiac surgery

This is a longitudinal observational study to explore postoperative cognitive recovery among older persons (aged 65 or older) undergoing elective or urgent cardiac surgery via sternotomy.


Locations(1)

Sahlgrenska University Hospital

Gothenburg, Sweden

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NCT06469515


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