Reducing Breathlessness With Dronabinol in COPD Patients

This study is testing whether dronabinol — a medication derived from cannabis — can help reduce severe breathlessness in people with advanced COPD (a serious lung disease) when standard treatments are no longer working well enough. Breathlessness is one of the most distressing symptoms for people with advanced COPD. **You may be eligible if...** - You have COPD classified as severe or very severe (GOLD stage 3 or 4) - Your breathlessness is severe even with the best available treatment - You are 18 years old or older - You understand and speak Danish - You are able to use effective contraception if you could become pregnant **You may NOT be eligible if...** - You have an active infection or COPD flare-up in the last month - You have been regularly using THC or CBD in the last month - Your life expectancy is less than 3 months - You are taking certain medications that interact with this drug (strong CYP3A4 inhibitors/inducers) - You have a current substance abuse problem - You have a significant psychiatric condition that increases risk Talk to your doctor to see if this trial is right for you.