Cannabis Clinical Trials

6 recruiting

Frequently Asked Questions

Common questions about Cannabis clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 30 trials

Recruiting
Not Applicable

Cannabis, Linked Emotions, and Adolescent Risk Study

DepressionSuicidal IdeationCannabis Use+1 more
Massachusetts General Hospital200 enrolled1 locationNCT06576076
Recruiting
Not Applicable

Preliminary Efficacy Trial of a Digital Intervention for Depression and Cannabis Use

Depression - Major Depressive DisorderMental DisorderCannabis Use Disorder
Massachusetts General Hospital80 enrolled1 locationNCT06878859
Recruiting
Not Applicable

Precision Brain Stimulation to Reduce Cannabis Craving in Schizophrenia

SchizophreniaCannabis UsePsychosis+1 more
Vanderbilt University Medical Center100 enrolled1 locationNCT07196462
Recruiting

Observational Study of THC Concentrations in Acute Cannabis-induced CNS Depression

Acute Cannabis-induced CNS Depression
Anebulo Pharmaceuticals36 enrolled1 locationNCT06017622
Recruiting
Phase 2

ARISTOCRAT: Blinded Trial of Temozolomide +/- Cannabinoids

Brain TumorGlioblastomaBrain Tumor, Recurrent+1 more
University of Birmingham120 enrolled22 locationsNCT05629702
Recruiting

SV2 PET Imaging With [11C]APP311

HealthyCannabis Use DisorderSchizophrenia and Other Psychotic Disorders
Yale University250 enrolled1 locationNCT03995121
Recruiting
Phase 1Phase 2

Mitigating PTSD-CUD After Sexual Assault

Cannabis Use DisorderPosttraumatic Stress Disorder
University of Nevada, Las Vegas68 enrolled6 locationsNCT05989841
Recruiting
Phase 1

HIV and Alcohol Research Center Focused on Polypharmacy (HARP) Pilot 2 (2nd HARP Pilot Intervention)

Cannabis UseAlcohol DrinkingHIV+1 more
Yale University100 enrolled1 locationNCT06513819
Recruiting
Not Applicable

Functional Outcomes of Cannabis Use (FOCUS) in Veterans With Posttraumatic Stress Disorder

PTSDCannabis-Related Disorder
VA Office of Research and Development40 enrolled1 locationNCT04565028
Recruiting
Phase 1

Use of a Generative AI (Gen-AI) Chatbot for Anxiety and Depression Among Persons With Cannabis Use

Depression, AnxietyAnxietyDepression - Major Depressive Disorder+1 more
Trustees of Dartmouth College15 enrolled1 locationNCT06920238
Recruiting

Longitudinal Study of Xenon-129 MRI Imaging Effects of Cannabis Smoking

Cannabis UseCannabis SmokingMarijuana Smoking+1 more
Western University, Canada200 enrolled1 locationNCT03909477
Recruiting
Not Applicable

The Neural Underpinnings of Depression and Cannabis Use in Young People Living With HIV

DepressionHIVCannabis Use Disorder
University of Miami280 enrolled1 locationNCT05453513
Recruiting
Phase 2

Gabapentin for Restoring GABA/Glutamate Homeostasis in Co-occurring Bipolar and Cannabis Use Disorders

Cannabis UseBipolar DisorderSchizoaffective Disorder, Bipolar Type+5 more
Medical University of South Carolina68 enrolled1 locationNCT05064319
Recruiting
Phase 1

Genetics of Cannabis Use Disorder and Cannabinoid Response in Humans

SchizophreniaCannabis Use Disorder
Yale University215 enrolled1 locationNCT06058702
Recruiting
Not Applicable

Modeling the Effects of Chronic Marijuana Use on Neuroinflammation and HIV-related Neuronal Injury

InflammationHIVCognition+2 more
Wake Forest University Health Sciences220 enrolled1 locationNCT04810858
Recruiting
Not Applicable

Genetic Counselling in the Prevention of Mental Health Consequences of Cannabis Use

SchizophreniaCannabis UseMajor Depressive Disorder+3 more
Nova Scotia Health Authority120 enrolled1 locationNCT03601026
Recruiting
Not Applicable

Neural and Psychiatric Consequences of Cannabis Use in Adolescents

DepressionCannabis Use
University of Miami280 enrolled2 locationsNCT06941298
Recruiting

Imaging Cannabinoid Receptors Using Positron Emission Tomography (PET) Scanning

Healthy ControlSchizophreniaPost Traumatic Stress Disorder+4 more
Yale University100 enrolled1 locationNCT01730781
Recruiting

Cannabis, HIV and Mental Processing Systems

HIV InfectionsCannabis
Washington University School of Medicine320 enrolled2 locationsNCT05430490
Recruiting
Phase 3

Reducing Breathlessness With Dronabinol in COPD Patients

COPDBreathlessnessCannabis
Vejle Hospital30 enrolled1 locationNCT06473701