RecruitingNCT06475261

Tissue Oximetry's Measurement in Cytoreductive Surgery With Hyperthermic Intraperitoneal Chemotherapy

Tissue Oximetry's Measurement in Cytoreductive Surgery With Hyperthermic Intraperitoneal Chemotherapy: Prospective Observational Study With Device


Sponsor

Fondazione Policlinico Universitario Agostino Gemelli IRCCS

Enrollment

50 participants

Start Date

Jul 27, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

Tissue oximetry obtained from peripheral muscle measures the state of tissue oxygenation of various organs and, as already widely described in the literature, can be used to measure the state of kidney's tissue oxygenation. However, there is no evidence in the existing scientific literature on the use of muscle tissue oximetry in patients undergoing cytoreductive surgery for ovarian cancer with hyperthermic intraperitoneal chemotherapy. The primary objective of our study is to evaluate whether there is a correlation between average intraoperative muscle tissue oximetry below 65% (a value which is considered critical in the literature for the resulting cellular damage) and postoperative renal damage in patients undergoing cytoreductive surgery with hyperthermic intraperitoneal chemotherapy for ovarian cancer.


Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 75 Years

Inclusion Criteria2

  • American Society Anesthesiologists (ASA) Classification 1-2
  • Cytoreductive surgery for ovarian cancer with laparoscopic or laparotomic technique with Hypertermic Intraperitoneal Chemotherapy.

Exclusion Criteria3

  • Age \< 18 years
  • ASA \> or = 3
  • Cytoreductive surgery without hyperthermic intraperitoneal chemotherapy

Interventions

DEVICETissue Oximetry with ForeSight

Evaluation of a correlation between average intraoperative muscle tissue oximetry and postoperative renal damage in patients undergoing cytoreductive surgery with HIPEC for ovarian cancer


Locations(1)

Policlinico "A. Gemelli" IRCCS

Rome, Italy

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NCT06475261


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