RecruitingNCT06480825

Application of Ultra-high Frequency Ultrasonography (UHFUS) to the Study of Gingival Tissues

Ulta-High Frequency Ultrasound Assessment of Normal Versus Gingivitis Affected Gingival Tissues


Sponsor

University of Pisa

Enrollment

40 participants

Start Date

Apr 2, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

Gingival inflammation triggered by the accumulation of bacterial is the primary risk factor for the development of periodontitis. Clinically, localized signs of inflammation limited to the gingiva, presence of significant bacterial plaque load, and stable attachment levels on the periodontium can be observed in course of gingivitis. The aim of the present study is to compare clinical aspects of gingival tissue in healthy patients versus patients with gingivitis to assess the ultrastructural variations present in course of inflammation. Patients with gingivitis and healthy controls will be enrolled. All patients will undergo ultra-high frequency ultrasonographic scans (70 MHz) of gingival tissue on three areas per dental arch (anterior, middle right, middle left). Gingival thickness, echogenicity, and vascularization assessed through resisitive index will be evaluated.


Eligibility

Min Age: 18 YearsMax Age: 70 Years

Inclusion Criteria5

  • males or females of age \> 18 years
  • presence of at least 20 teeth
  • full-mouth plaque score (FMPS) \>50%
  • FMBS \>30%
  • ability and willingness to give informed consent

Exclusion Criteria5

  • pregnancy or breastfeeding
  • pharmacological treatment with antinflammatory drugs, statins, or either local or systemic antibiotics (within the previous 30 days)
  • smoking habit
  • dental or periodontal condition requiring immediate treatment
  • refusal to be enrolled in the study

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Interventions

OTHERPerformance of ultrasonographic scan

Ultra-high frequency ultrasonographic scan of gingival tissues


Locations(2)

University of Pisa

Pisa, Italy, Italy

Department of Surgical, Medical and Molecular Pathology and Critical Care Medicine, University Hospital of Pisa

Pisa, Italy

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NCT06480825


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