RecruitingNot ApplicableNCT06489873

Lutein, Zeaxathin, and Fish Oil Supplementation

The Role of Lutein, Zeaxanthin, and Fish Oil on Cognitive Function and Bone Health in Healthy Adults


Sponsor

Texas A&M University

Enrollment

80 participants

Start Date

Feb 7, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this clinical trial is to learn the impact of lutein, zeaxanthin, and fish oil (LZF) supplementation in healthy adults. The main question it aims to answer is: Will supplementation with LZF improve macular pigment optical density (MPOD), cognitive performance and bone mass compared to controls after six months? Subjects with an MPOD \<.43 will significantly improve MPOD after 6-months of LZF supplementation. Consuming a LZFO supplement for 6-months will improve visual cognitive performance. Consuming a LZFO supplement for 6-months will improve bone density. Participants will be asked to take either a LZF supplement or placebo daily for 6 months.


Eligibility

Min Age: 18 YearsMax Age: 45 Years

Exclusion Criteria1

  • allergic to lutein, zeaxanthin, or fish oil, taking supplements with >6 mg lutein and/or >2 mg zeaxanthin for more than two months before study starts, MPOD between >.43, self-reported condition of vertigo, diabetic retinopathy, retinitis pigmentosa, optic neuropathy, retinal vascular occlusions, strabismus, autoimmune disorders related to visual health, currently pregnant or trying to become pregnant, history of concussion, vegan (due to gelatin in the placebo), and/or taking neuroactive medications, such as Ritalin, Adderall, antidepressants, etc.

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Interventions

DIETARY_SUPPLEMENTActive Comparator (Lutein, zeaxanthin, and fish oil supplement (LZF)

Each participant will be assigned to t a LZF supplement daily for six months

DIETARY_SUPPLEMENTPlacebo Comparator

Each participant will be assigned to take a placebo supplement daily for six months


Locations(1)

Gilchrist Building

College Station, Texas, United States

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NCT06489873


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