Bone Loss Clinical Trials

64 recruitingLast updated: July 17, 2026

There are 64 actively recruiting bone loss clinical trials across 30 countries. Studies span Not Applicable, Phase 4, Early Phase 1, Phase 2, Phase 3, Phase 1. Top locations include Cairo, Egypt, Murcia, Spain, Al Mansurah, Egypt. Updated daily from ClinicalTrials.gov.


Bone Loss Trials at a Glance

64 actively recruiting trials for bone loss are listed on ClinicalTrialsFinder across 6 cities in 30 countries. The largest study group is Not Applicable with 37 trials, with the heaviest enrollment activity in Cairo, Murcia, and Al Mansurah. Lead sponsors running bone loss studies include Menoufia University, Cairo University, and University of Valencia.

Browse bone loss trials by phase

Treatments under study

About Bone Loss Clinical Trials

Looking for clinical trials for Bone Loss? There are currently 31 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Bone Loss trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Bone Loss clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 64 trials

Recruiting
Not Applicable

Clinical Outcomes Study of the Nexel Total Elbow

Degenerative ArthritisElbow Joint DestructionPost-traumatic Lesions+7 more
Zimmer Biomet134 enrolled11 locationsNCT02469662
Recruiting
Not Applicable

Impact of Abutment Screw Torque on Marginal Bone Loss

Soft Tissues According to the Abutment TorqueMicroleakage Accordint to the Abutment TorquePROMS According to the Abutment Torque+1 more
University of Valencia30 enrolled1 locationNCT07234552
Recruiting
Not Applicable

Alveolar Ridge Preservation (ARP) in the Posterior Maxilla After the Extraction of Maxillary Molars

Alveolar Bone Loss
Virginia Commonwealth University40 enrolled1 locationNCT07433322
Recruiting
Not Applicable

Khoury's Bone Shell Technique Versus Titanium-Reinforced Polytetrafluoroethylene for Augmentation of Horizontal Deficiency in Posterior Mandible (Histomorphometry Analysis): A Randomized Clinical Trial

Alveolar Bone Loss in Posterior Mandible
British University In Egypt16 enrolled1 locationNCT07669792
Recruiting
Not Applicable

Outcomes of Ridge Splitting Versus Sausage Technique

Bone Loss, Alveolar
Beni-Suef University30 enrolled1 locationNCT07664605
Recruiting
Early Phase 1

Assessment of the Impact of Neocement Inject P® (Beta-Tricalcium Phosphate) on Bone Volume in Alveolar Ridge Preservation After Tooth Extraction

Tooth ExtractionTooth Extraction Site HealingAlveolar Bone Loss+1 more
Egas Moniz - Cooperativa de Ensino Superior, CRL30 enrolled1 locationNCT07638319
Recruiting
Phase 4

Bone, Exercise, Alendronate, and Caloric Restriction

Bone Loss
Wake Forest University Health Sciences900 enrolled2 locationsNCT05764733
Recruiting
Not Applicable

Peri-implant Tissues Changes for Different Abutment Shapes and Heights

Dental Implant-Abutment DesignsMarginal Bone Loss in Different Abutment DesignsSoft Tissue Management in Subcrestal Dental Implants
University of Valencia180 enrolled1 locationNCT07509281
Recruiting
Not Applicable

Effect of Collagen Membrane on Ridge Preservation

Tooth ExtractionAlveolar Bone LossDehiscence
Debora Dias30 enrolled1 locationNCT07580495
Recruiting
Not Applicable

Reduced Time Interval for Implant Placement After Extraction Socket Preservation Using the Vega Plus Implants

Tooth ExtractionAlveolar Bone Loss
Universidad Catolica Santiago de Guayaquil40 enrolled1 locationNCT07484685
Recruiting
Not Applicable

The Application of a Biphasic Calcium Sulfate Graft Material in Sinus Floor Elevation

Alveolar Bone LossEdentulism Nos
Semmelweis University40 enrolled1 locationNCT06533397
Recruiting

Impact of Alveolar Ridge Preservation on the Potential Need for Sinus Floor Elevation: A 10-year Retrospective Radiographical Study

Alveolar Bone LossAlveolar Bone AtrophyAlveolar Ridge Preservation+2 more
Saint-Joseph University130 enrolled1 locationNCT07526129
Recruiting
Phase 1Phase 2

Evaluation of Stem Cell Exosomes Versus Platelet-Rich Fibrin in Tooth Extraction Socket Healing

Tooth ExtractionAlveolar Bone LossBone Regeneration
Al Salam University40 enrolled1 locationNCT07508033
Recruiting
Not Applicable

Assessment of Labial Plate Thickness After Immediate Implant Placement Using Two Different Xenografts in the Esthetic Zone

Tooth Extraction Status NosImmediate Implant PlacementAlveolar Bone Loss
Basma Gamal Mohamed Ahmed26 enrolled1 locationNCT07449806
Recruiting
Not Applicable

Immediate Implant Placement With Autogenous Maxillary Tuberosity Graft in the Esthetic Zone

Alveolar Bone LossEsthetic Zone Implant Rehabilitation
University of Medicine and Pharmacy at Ho Chi Minh City15 enrolled1 locationNCT07460076
Recruiting
Not Applicable

Comparison of Bone Microarchitecture Analysed by HRpQCT and pQCT in Pathologies With Bone Loss and/or Muscle Loss

Osteoporosis RiskBone Loss
Centre Hospitalier Universitaire de Saint Etienne1,000 enrolled1 locationNCT06541548
Recruiting

Innovative Technologies for Salvage Procedures of Failed Treatments of Osteoarthritis: Biomimetics Solutions (CustomPN)

Bone LossArthroplasty ComplicationsHip Prosthesis Infection
Istituto Ortopedico Rizzoli15 enrolled1 locationNCT06527664
Recruiting
Phase 3

Bisphosphonate Use to Mitigate Bone Loss Secondary to Bariatric Surgery

Bone Loss
Wake Forest University Health Sciences200 enrolled1 locationNCT04922333
Recruiting
Not Applicable

Comparison of Customized Allogenic Versus Autogenous Bone Block Graft for Alveolar Ridge Augmentation

Alveolar Bone Loss
Medical University of Graz26 enrolled1 locationNCT07419269
Recruiting
Not Applicable

Minimally Invasive Sinus Lift Through the Interradicular Septum

Surgical Procedure, UnspecifiedBone LossBone Loss, Age-related+1 more
Universidad de Murcia20 enrolled1 locationNCT05237570