A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence
Elacestrant Versus Standard Endocrine Therapy in Women and Men With Node-positive, Estrogen Receptor-positive, HER2-negative, Early Breast Cancer With High Risk of Recurrence-A Global, Multicenter, Randomized, Open-label Phase 3 Study
Stemline Therapeutics, Inc.
4,220 participants
Sep 27, 2024
INTERVENTIONAL
Conditions
Summary
The primary goal of this study is to evaluate the effectiveness of elacestrant versus standard endocrine therapy in participants with node-positive, Estrogen Receptor-positive (ER+), Human Epidermal Growth Factor-2 negative (HER2-) early breast cancer with high risk of recurrence.
Eligibility
Inclusion Criteria4
- Histopathologically or cytologically confirmed ER-positive (≥ 10% by immunohistochemistry \[IHC\]), HER2-negative \[IHC = 0, 1+, 2 and in situ hybridization \[ISH\]-negative)\] on tumor biopsy or final surgical pathology specimen early stage resected invasive breast cancer without evidence of recurrence or distant metastases, per local laboratory, according to the American Society of Clinical Oncology (ASCO)/College of American Pathologists (CAP) guidelines
- Participants considered at high risk of recurrence at initial staging
- Participants who have received at least 24 months but not more than 60 months of endocrine therapy (AIs or tamoxifen) with or without a CDK 4 and CKD 6 inhibitor (CDK4/6i)
- Participants who received prior CDK4/6i or a poly adenosine diphosphate-ribose polymerase (PARP) inhibitor must have already completed or discontinued these treatments.
Exclusion Criteria4
- Participants with inflammatory breast cancer
- History of any prior (ipsilateral and/or contralateral) invasive breast cancer
- Participant with history of malignancy within 3 years of the date of randomization, except for adequately treated basal or squamous cell skin cancer, superficial bladder cancer or carcinoma in situ of the cervix
- Participants who have had more than a 6-month continuous interruption of prior SoC adjuvant endocrine therapy or who are off current adjuvant endocrine therapy more than 6 months prior to randomization
Interventions
Administered as oral tablets
Administered as oral tablets
Administered as oral tablets
Administered as oral tablets
Administered as oral tablets
Locations(524)
Southern Cancer Center, PC
Daphne, Alabama, United States
Ironwood Cancer and Research Centers
Chandler, Arizona, United States
Banner MD Anderson Cancer Center
Gilbert, Arizona, United States
Mayo Clinic
Scottsdale, Arizona, United States
Arizona Clinical Research Center, Inc.
Tucson, Arizona, United States
University of Arizona Cancer Center
Tucson, Arizona, United States
Highlands Oncology Group, PA
Springdale, Arkansas, United States
Comprehensive Blood & Cancer Center
Bakersfield, California, United States
UCSF Cancer Center Berkeley
Berkeley, California, United States
City of Hope National Medical Center
Duarte, California, United States
UCSF Wash Cancer CNTR
Fremont, California, United States
UC San Diego Moores Cancer Center
La Jolla, California, United States
Helios Clinical Research
Long Beach, California, United States
Cancer and Blood Research Center, LLC
Los Alamitos, California, United States
USC/Norris Comprehensive Cancer Center
Los Angeles, California, United States
UCLA Department of Medicine - Hematology/Oncology
Los Angeles, California, United States
Hoag Memorial Hospital Presbyterian
Newport Beach, California, United States
UC Irvine Health, Chao Family Comprehensive Cancer Center
Orange, California, United States
Stanford Women's Cancer Center
Palo Alto, California, United States
Dignity Health dba Health Research Institute
Sacramento, California, United States
Sutter Institute for Medical Research
Sacramento, California, United States
UCSF Zuckerberg SF General
San Francisco, California, United States
University of California, San Francisco (UCSF)
San Francisco, California, United States
Southern California Kaiser Medical Center-San Marcos Medical
San Marcos, California, United States
UCSF Cancer Center San Mateo
San Mateo, California, United States
Sansum Clinic
Solvang, California, United States
Torrance Memorial Physician Network- Cancer Care
Torrance, California, United States
St.Joseph Hospital- Cancer Centers of Colorado
Denver, Colorado, United States
Rocky Mountain Cancer Centers, LLP
Lone Tree, Colorado, United States
AHMG Hematology and Oncology
Parker, Colorado, United States
Cancer Care at CommonSpirit St. Anthony North Hospital
Westminster, Colorado, United States
Yale New Haven Hospital- Yale Cancer Center
New Haven, Connecticut, United States
MedStar Washington Hospital Center
Washington D.C., District of Columbia, United States
The George Washington Medical Faculty Associates
Washington D.C., District of Columbia, United States
Boca Raton Regional Hospital (BRRH) - Lynn Cancer Institute
Boca Raton, Florida, United States
Florida Cancer Specialists
Fort Myers, Florida, United States
Mayo Clinic
Jacksonville, Florida, United States
Helios Clinical
Lakeland, Florida, United States
Miami Cancer Institute at Baptist Health Inc.
Miami, Florida, United States
University of Miami
Miami, Florida, United States
AdventHealth Orlando Infusion Center
Orlando, Florida, United States
Cancer Care Centers of Brevard (CCCB) - Palm Bay
Palm Bay, Florida, United States
Memorial Healthcare System
Pembroke Pines, Florida, United States
Ascension Sacred Heart
Pensacola, Florida, United States
Miami Cancer Institute at Plantation
Plantation, Florida, United States
Florida Cancer Specialists
St. Petersburg, Florida, United States
Comprehensive Hematology Oncology
St. Petersburg, Florida, United States
Moffitt Cancer Center
Tampa, Florida, United States
Florida Cancer Specialists
West Palm Beach, Florida, United States
Cleveland Clinic Florida
Weston, Florida, United States
University Blood & Cancer Center, LLC
Athens, Georgia, United States
Winship Cancer Institute
Atlanta, Georgia, United States
Northside Hospital
Atlanta, Georgia, United States
Kaiser Permanente Hawaii Moanalua Medical Center
Honolulu, Hawaii, United States
Illinois Cancer Specialists
Arlington Heights, Illinois, United States
Northwestern Memorial Hospital
Chicago, Illinois, United States
RUSH MD Anderson Cancer Center
Chicago, Illinois, United States
Northwest Cancer Centers, PC
Dyer, Indiana, United States
Mission Cancer and Blood
Des Moines, Iowa, United States
Cancer Center of Kansas
Wichita, Kansas, United States
University Medical Center-New Orleans
New Orleans, Louisiana, United States
Mercy Medical Center
Baltimore, Maryland, United States
Ascension St. Agnes Hospital
Baltimore, Maryland, United States
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Baltimore, Maryland, United States
Maryland Oncology Hematology, P.A.
Columbia, Maryland, United States
Massachusetts General Hospital
Boston, Massachusetts, United States
Boston Medical Center
Boston, Massachusetts, United States
Beth Israel Deaconess Medical Center
Boston, Massachusetts, United States
Dana Farber Cancer Institute
Boston, Massachusetts, United States
Mass General North Shore Cancer Center
Danvers, Massachusetts, United States
Dana Farber Cancer Institute at Foxborough
Foxborough, Massachusetts, United States
Dana Farber Cancer Institute - Merrimack Valley
Methuen, Massachusetts, United States
Dana-Farber Cancer Institute at Milford Regional
Milford, Massachusetts, United States
Mass General Cancer Center at Newton-Wellesley Hospital's Vernon Cancer Center
Newton, Massachusetts, United States
Dana-Farber/Brigham and Women's Cancer Center (DF/BWCC) in Clinical Affiliation with South Shore Hospital
South Weymouth, Massachusetts, United States
Mass General - North Shore Cancer Center
Waltham, Massachusetts, United States
The Cancer & Hematology Centers
Grand Rapids, Michigan, United States
Mayo Clinic Health System - Albert Lea
Albert Lea, Minnesota, United States
Mayo Clinic - Mankato
Mankato, Minnesota, United States
Allina Health Cancer Institute - Abbott Northwestern Hospital
Minneapolis, Minnesota, United States
Mayo Clinic
Rochester, Minnesota, United States
Siteman Cancer Center
St Louis, Missouri, United States
NHO Revive Research Institute LLC
Lincoln, Nebraska, United States
Oncology Hematology West, PC dba Nebraska Cancer Specialists - Legacy
Omaha, Nebraska, United States
University of Nebraska Medical Center
Omaha, Nebraska, United States
MD Anderson Cancer Center at Cooper
Camden, New Jersey, United States
Summit Medical Group
Florham Park, New Jersey, United States
John Theurer Ctr-Hackensack UMC
Hackensack, New Jersey, United States
Rutgers Cancer Institute
New Brunswick, New Jersey, United States
Exigent Research LLC/New Mexico Oncology Hematology Consultants Ltd.
Albuquerque, New Mexico, United States
Kings County Hospital Center
Brooklyn, New York, United States
Hematology Oncology Associates of Central New York, PC
East Syracuse, New York, United States
Cayuga Medical Center
Ithaca, New York, United States
NYU Langone Hospital-Long Island
Mineola, New York, United States
The Blavatnik Family - Chelsea Medical Center at Mount Sinai
New York, New York, United States
Laura and Isaac Perlmutter Cancer Center/NYU Langone Health
New York, New York, United States
Mount Sinai West
New York, New York, United States
Icahn School of Medicine Mount Sinai
New York, New York, United States
Columbia University Medical Center
New York, New York, United States
University of Rochester Medical
Rochester, New York, United States
Stony Brook University Cancer Center
Stony Brook, New York, United States
Clinical Research Alliance, Inc.
Westbury, New York, United States
Duke Cancer Institute
Durham, North Carolina, United States
Cape Fear Valley Medical Center
Fayetteville, North Carolina, United States
Cone Health Cancer Center at Wesley Long
Greensboro, North Carolina, United States
Miami Valley Hospital South
Centerville, Ohio, United States
MetroHealth
Cleveland, Ohio, United States
Cleveland Clinic
Cleveland, Ohio, United States
Oncology_Hematology Care Clinical Trials, LLC
Fairfield, Ohio, United States
Oklahoma Cancer Specialists and Research Institute (OCSRI) - Tulsa Cancer Center
Tulsa, Oklahoma, United States
Providence Cancer Institute Franz Clinic
Portland, Oregon, United States
Oregon Oncology Specialists
Salem, Oregon, United States
Northwest Cancer Specialists, P.C.
Tigard, Oregon, United States
Lehigh Valley Health Network - Cedar Crest
Allen, Pennsylvania, United States
Consultants In Medical Oncology and Hematology, P.C.
Broomall, Pennsylvania, United States
Penn State Milton S. Hershey Medical Center
Hershey, Pennsylvania, United States
Holy Redeemer Hospital And Medical Center
Meadowbrook, Pennsylvania, United States
Alliance Cancer Specialists, PC
Media, Pennsylvania, United States
Lankenau Medical Center
Wynnewood, Pennsylvania, United States
Cancer Care Associates of York, Inc.
York, Pennsylvania, United States
Rhode Island Hospital
Providence, Rhode Island, United States
Hollings Cancer Center
Charleston, South Carolina, United States
Avera Cancer Institute
Sioux Falls, South Dakota, United States
Baptist Cancer Center
Memphis, Tennessee, United States
SCRI Oncology Partners
Nashville, Tennessee, United States
Tennessee Oncology, PLLC
Nashville, Tennessee, United States
Henry - Joyce Cancer Clinic
Nashville, Tennessee, United States
Hendrick Cancer Center
Abilene, Texas, United States
Texas Oncology-Northeast Texas
Allen, Texas, United States
Texas Oncology - DFW
Dallas, Texas, United States
Oncology Consultants, P.A.
Houston, Texas, United States
The University of Texas MD Anderson Cancer Center
Houston, Texas, United States
Harris Health System - Smith Clinic
Houston, Texas, United States
O'Quinn Medical Tower - McNair Campus
Houston, Texas, United States
Covenant Children's Hospital- Joe Arrington Cancer Research and Treatment Center
Lubbock, Texas, United States
Texas Oncology - San Antonio
New Braunfels, Texas, United States
Texas Oncology-Gulf Coast
Pearland, Texas, United States
Mays Cancer Center
San Antonio, Texas, United States
Texas Oncology- Central South
Weslaco, Texas, United States
Utah Cancer Specialists
Salt Lake City, Utah, United States
Huntsman Cancer Institute, University of Utah
Salt Lake City, Utah, United States
University of Vermont Medical Center
Burlington, Vermont, United States
Inova Schar Cancer Institute
Fairfax, Virginia, United States
Virginia Oncology Associates
Newport News, Virginia, United States
Virginia Cancer Institute
Richmond, Virginia, United States
Oncology & Hematology Associates of Southwest Virginia, Inc
Wytheville, Virginia, United States
Vista Oncology
Olympia, Washington, United States
Virginia Mason Medical Center
Seattle, Washington, United States
Swedish Cancer Institute
Seattle, Washington, United States
Fred Hutchinson Cancer Center
Seattle, Washington, United States
Cancer Care Northwest
Spokane Valley, Washington, United States
MultiCare Cancer Institute - Tacoma
Tacoma, Washington, United States
Northwest Medical Specialties PLLC
Tacoma, Washington, United States
Mayo Clinic Health System - Eau Claire
Eau Claire, Wisconsin, United States
Mayo Clinic Health System - La Crosse
La Crosse, Wisconsin, United States
University of Wisconsin Carbone Cancer Center- University Hospital
Madison, Wisconsin, United States
UW Cancer Center at ProHealth Care
Waukesha, Wisconsin, United States
(COIBA)Centro de Oncologia e Investigacion Buenos Aires
Berazategui, Buenos Aires, Argentina
Fundacion Respirar
Buenos Aires, Buenos Aires F.D., Argentina
Organizacion Medica de Investigacion (OMI)
Buenos Aires, Buenos Aires F.D., Argentina
Centro de Investigación CIPREC
C.a.b.a., Buenos Aires F.D., Argentina
Centro Oncológico Korben
CABA, Buenos Aires F.D., Argentina
Centro Medico Privado CEMAIC
Córdoba, Córdoba Province, Argentina
Inst Med Fund Estudios Clinicos
Rosario, Santa Fe Province, Argentina
Instituto de Oncologia de Rosario
Rosario, Santa Fe Province, Argentina
Clinica Adventista Belgrano
Buenos Aires, Tucumán Province, Argentina
Instituto Argentino de Diagnostico y Tratamiento
Buenos Aires, Argentina
Centro Oncologico de Excelencia
San Juan, Argentina
St Vincent's Hospital Sydney
Darlinghurst, New South Wales, Australia
Lake Macquarie Private Hospital - Oncology
Gateshead, New South Wales, Australia
St George Hospital - Medical Oncology
Kogarah, New South Wales, Australia
Lismore Base Hospital - Cancer Care , Haematology Unit
Lismore, New South Wales, Australia
Macquarie University
Macquarie Park, New South Wales, Australia
Mater Hospital Sydney
North Sydney, New South Wales, Australia
Westmead Hospital
Westmead, New South Wales, Australia
Icon Cancer Centre Townsville
Hyde Park, Queensland, Australia
Icon Cancer Centre Southport
Southport, Queensland, Australia
Icon Cancer Centre Wesley
Auchenflower, Quuensland, Australia
Cancer Research SA
Adelaide, South Australia, Australia
Royal Adelaide Hospital - Oncology
Adelaide, South Australia, Australia
Flinders Medical Centre
Bedford Park, South Australia, Australia
Icon Cancer Centre Kurralta Park
Kurralta Park, South Australia, Australia
The Queen Elizabeth Hospital
Woodville, South Australia, Australia
Box Hill Hospital
Box Hill, Victoria, Australia
Monash Medical Centre
Clayton, Victoria, Australia
Northern Hospital
Epping, Victoria, Australia
Goulburn Valley Health
Shepparton, Victoria, Australia
Breast Cancer Research Centre
Nedlands, Western Australia, Australia
Austin Health
Heidelberg, Australia
Icon Cancer Centre Hobart
Hobart, Australia
Mid North Coast Cancer Institute
Port Macquarie, Australia
Universitätsklinikum Krems
Krems, Lower Austria, Austria
Universitatsklinikum St. Polten
Sankt Pölten, Lower Austria, Austria
LKH Hochsteiermark
Leoben, Styria, Austria
Brustgesundheitszentrum Süd
Weiz, Styria, Austria
Hanusch Krankenhaus
Vienna, Austria
Algemeen Ziekenhuis Klina
Brasschaat, Antwerpen, Belgium
Clnique Saint Pierre Ottignies - Oncologie-Hématologie
Ottignies, Brabant Wallon, Belgium
Edith Cavell Inter-regional Hospital Centre (CHIREC) - Delta Hospital
Aalst, Brussels Capital, Belgium
CHU Saint-Pierre
Brussels, Brussels Capital, Belgium
Grand Hopital de Charleroi - Site Les Viviers
Charleroi, Hainaut, Belgium
Jessa Ziekenhuis - Campus Virga Jesse - Medische Oncologie
Hasselt, Limburg, Belgium
VITAZ Campus Sint-Niklaas Moerland
Sint-Niklaas, Oost-Vlaanderen, Belgium
UZ Leuven
Leuven, Vlaams Brabant, Belgium
Institut Jules Bordet
Brussels, Belgium
CHU De Liège - Oncologie Médicale
Liège, Belgium
CHC - Oncologie - Hémato-Immunopatho
Liège, Belgium
CHU UCL Namur - Site Ste Elisabeth - Oncologie
Namur, Belgium
Instituto D'Or de Pesquisa e Ensino (Oncocentro Servicos Medicos e Hospitalares LTDA)
Fortaleza, Ceará, Brazil
Centro de Pesquisas Clínicas em Oncologia
Cachoeiro de Itapemirim, Espírito Santo, Brazil
CEDOES - Centro de Pesquisa Clinica e Diagnostico do Espirito Santo LTDA
Vitória, Espírito Santo, Brazil
Hospital Araujo Jorge
Goiânia, Goiás, Brazil
CETUS Oncologia S.A
Belo Horizonte, Minas Gerais, Brazil
Hospital Santa Cruz Sociedade Anonima
Curitiba, Paraná, Brazil
Centro Integrado Oncologia Curitiba
Curitiba, Paraná, Brazil
Instituto de Câncer de Londrina
Londrina, Paraná, Brazil
CTO Centro de Tratamento Oncologico LTDA
Belém, Pará, Brazil
Hospital da Fundacao Oswaldo Aranha
Volta Redonda, Rio de Janeiro, Brazil
Sociedade Beneficência e Caridade de Lajeado (Hospital Bruno Born)
Lajeado, Rio Grande do Sul, Brazil
Futtura Oncologia
Porto Alegre, Rio Grande do Sul, Brazil
Centro Gaucho Integrado de Oncologia, Hematologia, Ensino e Pesquisa - Hospital Mae de Deus
Porto Alegre, Rio Grande do Sul, Brazil
Fundação PIO XII - Hospital de Amor Amazônia
Porto Velho, Rondônia, Brazil
Centro de Pesquisas Oncologicas - CEPON
Florianópolis, Santa Catarina, Brazil
Clinica de Neoplasias Litoral
Itajaí, Santa Catarina, Brazil
Fundação Pio XII - Hospital de Amor de Barretos
Barretos, São Paulo, Brazil
Instituto do Cancer do Estado de Sao Paulo (ICESP)
Barueri, São Paulo, Brazil
Universidade de Sao Paulo (USP) - Hospital das Clinicas da Faculdade de Medicina de Ribeirao Preto (HCFMRP)
Ribeirão Preto, São Paulo, Brazil
Hospital de Base de São José do Rio Preto - CIP
São José do Rio Preto, São Paulo, Brazil
Instituto Brasileiro de Controle do Cancer - ibcc - Hematology / Oncology
São Paulo, São Paulo, Brazil
PUCRS - Hospital São Lucas
Porto Alegre, Brazil
Instituto Nacional do Cancer - INCA-HC III
Rio de Janeiro, Brazil
Instituto de Educacao, Pesquisa e Gestao em Saude
Rio de Janeiro, Brazil
Clínica de Pesquisas e Centro de Estudos em Oncologia Ginecológica e Mamária Ltda
São Paulo, Brazil
A.C.Camargo Cancer Center
São Paulo, Brazil
Instituto de Assistencia Medica ao Servidor Publico Estadual (IAMSPE)
São Paulo, Brazil
Onco Star SP Oncologia LTDA (Onco Star)
São Paulo, Brazil
Hospital Universitario y Politecnico La Fe - Oncología Médica
Valência, Brazil
BC Cancer -Surrey
Surrey, British Columbia, Canada
BC Cancer Agency
Vancouver, British Columbia, Canada
Royal Victoria Regional Health Centre; c/o Oncology Clinical Trials
Barrie, Ontario, Canada
London Health Sciences Centre
London, Ontario, Canada
St. Michaels Hospital
Toronto, Ontario, Canada
Mount Sinai Hospital - Study Supplies
Toronto, Ontario, Canada
Jewish General Hospital
Montreal, Quebec, Canada
Centre hospitalier régional de Lanaudière
Saint-Charles-Borromée, Quebec, Canada
Regional Hospital Saint-Jerome
Saint-Jérôme, Quebec, Canada
Hôpital du Saint-Sacrement
Québec, Canada
Masarykuv onkologicky ustav - Klinika komplexni onkol. pece
Brno, Brno-město, Czechia
Multiscan s.r.o.
Hořovice, Stredoceský Kraj, Czechia
FN Kralovske Vinohrady - Radioterapeuticka a onkologicka klinika
Prague, Czechia
Fakultni Thomayerova nemocnice - Onkologicka klinika
Prague, Czechia
Hillerod Hospital
Hillerød, Capital, Denmark
Odense Universitetshospital - Oncology
Odense, Region Syddanmark, Denmark
Soenderborg Sygehus
Sønderborg, Region Syddanmark, Denmark
Docrates Mehiläinen Syöpäsairaala, Mehiläinen Oy
Helsinki, Etelä-Suomen Lääni, Finland
Tampere University Hospital
Tampere, Etelä-Suomen Lääni, Finland
Turku University Hospital
Turku, Etelä-Suomen Lääni, Finland
Helsinki University Central Hospital (HUCH) - Meilahden Sair
Helsinki, Länsi-Suomen Lääni, Finland
Vaasa Central Hospital
Vaasa, Länsi-Suomen Lääni, Finland
Kuopio University Hospital, Pohjois-Savon hyvinvointialue
Kuopio, Northern Savonia, Finland
Centre Hospitalier Regional et Universitaire (CHRU) de Besancon - L'Hopital Jean Minjoz
Besançon, Alpes-Maritimes, France
Polyclinique Saint George
Nice, Alpes-Maritimes, France
Inst Cancerologie Strasbourg Europe
Strasbourg, Alsace, France
CHU de Grenoble
Grenoble, Auvergne-Rhône-Alpes, France
Centre de cancerologie Les Dentellieres
Valenciennes, Hauts-de-France, France
Ct Oncologie Radiotherapie CORT 37
Chambray-lès-Tours, Indre-et-Loire, France
Hopital Universitaire Dupuytren
Limoges, Limousin, France
Polyclinique de Blois
La Chaussée-Saint-Victor, Loir-et-Cher, France
Institut de Cancerologie de l'Ouest - Oncology
Saint-Herblain, Loire-Atlantique, France
ICONE
Bezannes, Marne, France
CRLCC Jean Godinot
Reims, Marne, France
Centre Jean Perrin
Clermont-Ferrand, Puy-de-Dôme, France
Centre Hospitalier De Pau
Pau, Pyrénées-Atlantiques, France
Institut de Cancerologie Bourgogne
Dijon, Saône-et-Loire, France
CHU Amiens - Picardie Site Sud
Amiens, Somme, France
Institut Gustave Roussy
Villejuif, Val-de-Marne, France
CHI De Fréjus / Saint-Raphael
Fréjus, Var, France
Institut Sainte Catherine
Avignon, Vaucluse, France
CHD Vendee
La Roche-sur-Yon, Vendée, France
Centre Hospitalier Universitaire De Poitiers - Pôle Régional de Cancérologie
Poitiers, France
Institut de Cancérologie de Lorraine
Vandœuvre-lès-Nancy, France
Hopital Tenon
Paris, Île-de-France Region, France
Praxisklinik am Rosengarten
Mannheim, Baden-Wurttemberg, Germany
Universitätsmedizin Mannheim (UMM)
Mannheim, Baden-Wurttemberg, Germany
Hämatologie-Onkologie Zentrum MVZ
Augsburg, Bavaria, Germany
Universitätsklinikum Augsburg
Augsburg, Bavaria, Germany
Studienzentrale für das MVZ e.K
Eggenfelden, Bavaria, Germany
Universitaetsklinikum Erlangen
Erlangen, Bavaria, Germany
LMU - Klinikum Innenstadt
München, Bavaria, Germany
Klinikum rechts der Isar, TUM München
München, Bavaria, Germany
Caritas-Krankenhaus St. Josef - Frauenheilkunde und Geburtshilfe
Regensburg, Bavaria, Germany
Immanuel Klinik Rüdersdorf
Rüdersdorf, Brandenburg, Germany
'Klinikum Esslingen GmbH
Esslingen am Neckar, Esslingen a.N., Germany
'Schwerpunktpraxis Fuer Gynaekologie und Onkologie
Brandenburg, Fuerstenwalde /Spree, Germany
Klinikum Frankfurt Höchst GmbH
Frankfurt am Main, Hesse, Germany
Marienhospital Bottrop gGmbH
Bottrop, North Rhine-Westphalia, Germany
GynOnco Duesseldorf
Düsseldorf, North Rhine-Westphalia, Germany
Evang. Kliniken Essen-Mitte
Essen, North Rhine-Westphalia, Germany
Evangelisches Krankenhaus Bethesda
Mönchengladbach, North Rhine-Westphalia, Germany
Marien Hospital Witten
Witten, North Rhine-Westphalia, Germany
Klinikum Worms gGmbH
Worms, Rhineland-Palatinate, Germany
Universitätsklinikum des Saarlandes
Homburg/Saar, Saarland, Germany
Gemeinschaftspraxis Haematologie - Onkologie
Dresden, Saxony, Germany
University Hospital Of Leipzig - Frauen- und Kindermedizin
Leipzig, Saxony, Germany
Universitätsklinikum Schleswig-Holstein, Campus Lübeck
Lübeck, Schleswig-Holstein, Germany
Praxisklinik Krebsheilkunde
Berlin, Germany
Helios Klinikum Berlin-Buch
Berlin, Germany
Charite-Universitaetsmedizin Berlin - Campus Charite Mitte (CCM)
Berlin, Germany
Staedtisches Klinikum Dessau
Dessau, Germany
Mammazentrum Hamburg MVZ GbR
Hamburg, Germany
Hong Kong Sanatorium & Hospital (HKSH)
Happy Valley, Hong Kong
Pamela Youde Nethersole Eastern Hospital
Hong Kong, Hong Kong
Queen Mary Hospital - Clinical Oncology
Hong Kong, Hong Kong
Prince of Wales Hospital (PWH) - The Chinese University of Hong Kong (CUHK) - Clinical Oncology
Shatin, Hong Kong
University Of Pécs - Oncology dept.
Pécs, Baranya, Hungary
Békés Megyei Központi Kórház Pándy Kálmán Tagkórház - Oncology
Gyula, Bekes County, Hungary
Bacs-Kiskun Varmegyei Oktatakorhaz
Kecskemét, Bács-Kiskun county, Hungary
Debreceni Egyetem Klinikai Kozpont
Debrecen, Hajdú-Bihar, Hungary
Nograd Varmegyei Szent Lazar Korhaz
Salgótarján, Szabolcs-Szatmár-Bereg, Hungary
Zala Vármegyei Szent Rafael Korhaz - Onkologiai Osztaly
Zalaegerszeg, Zala County, Hungary
Budapesti Uzsoki Utcai Korhaz
Budapest, Hungary
Ospedale Casa Sollievo della Sofferen IRCCS, Opera di San Pio da Pietrelcina
San Giovanni Rotondo, Apulia, Italy
AOU Cagliari
Monserrato, Cagliari, Italy
Ist.Oncologico del Mediterraneo
Viagrande, Catania, Italy
SSD Oncologia Medica Zamagni, IRCCS Azienda Ospedaliero- Universitaria di Bologna, Policlinico di Sant'Orsola
Bologna, Emilia-Romagna, Italy
IRST Dino Amadori IRCCS
Meldola, Forli-Cesena, Italy
IRCCS San Gerardo dei Tintori
Monza, Monza E Brianza, Italy
Azienda Sanitaria Locale Napoli 2 Nord
Frattamaggiore, Napoli, Italy
Centro di Riferimento Oncologico, IRCCS
Aviano, Pordenone, Italy
Fond. Piemonte per l'Oncologia - Istituto di Candiolo IRCCS
Candiolo, Torino, Italy
Divisione di Oncologia Medica ASST Spedali Civili di Brescia
Brescia, Italy
Ospedale di Cremona, ASST Cremona
Cremona, Italy
SOD Radioterapia Oncologica, AOU Careggi
Florence, Italy
Ospedale San Martino IRCCS
Genova, Italy
Azienda Unità Sanitaria Locale Toscana Nord Ovest
Livorno, Italy
Ospedale Generale Provinciale di Macerata
Macerata, Italy
Istituto Nazionale dei Tumori,IRCCS
Milan, Italy
Istituto Europeo di Oncologia IRCCS
Milan, Italy
S. C. Oncologia, Centro Oncologico Modenese (COM) - A.O.U. di Modena -Policlinico di Modena
Modena, Italy
Azienda Ospedaliera Universitaria Federico II
Napoli, Italy
IRCCS Istituto Nazionale Tumori Fondazione Pascale
Napoli, Italy
UOC Oncologia - A.O.R.N. "A. Cardarelli"
Napoli, Italy
AOU Maggiore della Carità - Oncologia
Novara, Italy
Istituto Oncologico Veneto
Padua, Italy
IRCCS ICS Maugeri
Pavia, Italy
IRCCS Policlinico San Matteo, Università degli studi di Pavia
Pavia, Italy
Ospedale Santa Maria Della Misericordia
Perugia, Italy
PO S.Chiara, AOU Pisana
Pisa, Italy
PO S Carlo, Azienda Ospedaliera Regionale San Carlo - Oncologia
Potenza, Italy
Azienda USL Toscana Centro
Prato, Italy
Azienda Unita Sanitaria Locale della Romagna
Rimini, Italy
Irccs Crob
Rionero in Vulture, Italy
Fondazione PU Campus Biomedico
Roma, Italy
U.O. Ginecologia Oncologica - Fondazione Policlinico A. Gemelli
Roma, Italy
IRCCS Istituto Nazionale Tumori Regina Elena,UOSD Sperimentazioni di fase IV
Roma, Italy
AOCO S. Giovanni - Addolorata
Roma, Italy
Azienda Ospedaliero Universitaria Di Sassari
Sassari, Italy
Azienda Ospedaliera Universitaria Senese
Siena, Italy
SOC Oncologia - P.O. "Santa Maria della Misericordia"
Udine, Italy
Ospedale Sacro cuore Don Calabria- Negrar di Valpolicella
Verona, Italy
Universiti Sains Malaysia /ID# 200101
Kota Bharu, Kelantan, Malaysia
Pantai Hospital Kuala Lumpur
Kuala Lumpur, Kuala Lumpur, Malaysia
UKM Medical Centre
Kuala Lumpur, Kuala Lumpur, Malaysia
Beacon Hospital
Kuala Lumpur, Kuala Lumpur, Malaysia
Universiti Malaya Medical Centre
Kuala Lumpur, Kuala Lumpur, Malaysia
Institut Kanser Negara
Putrajaya, Kuala Lumpur, Malaysia
Hospital Raja Permaisuri Bainun
Ipoh, Perak, Malaysia
Hospital Pulau Pinang - Rheumatology
George Town, Pulau Pinang, Malaysia
Institut Perubatan & Pergigian Termaju (IPPT) - USM (Kepala Batas, Pulau Pinang)
Kepala Batas, Pulau Pinang, Malaysia
Hospital Sultan Ismail
Johor Bahru, Malaysia
Hospital Kuala Lumpur
Kuala Lumpur, Malaysia
Mahkota Medical Center
Malacca, Malaysia
Elisabeth-TweeSteden Ziekenhuis
Tilburg, North Brabant, Netherlands
Albert Schweitzer Ziekenhuis Locatie Dordwijk
Dordrecht, South Holland, Netherlands
Haga Ziekenhuis - Internal Medicine
The Hague, South Holland, Netherlands
Catharina Ziekenhuis
Eindhoven, Netherlands
Pratia Poznan
Poznan, Greater Poland Voivodeship, Poland
Wielkopolskie Centrum Onkologii Oddzial Onkologii Klinicznej i Immunoonkologii
Poznan, Greater Poland Voivodeship, Poland
Dolnoslaskie Centrum Onkologii, Pulmonologii i Hematologii - Oddzial Onkologii Klinicznej/Chemioterapii
Wroclaw, Lower Silesian Voivodeship, Poland
Centrum Onkologii Ziemi Lubelskiej im. sw. Jana z Dukli - I Oddzial Onkologii Klinicznej
Lublin, Lubusz Voivodeship, Poland
Europejskie Centrum Zdrowia Otwock, Szpital im. F. Chopina - Oddział Onkologii Klinicznej
Otwock, Masovian Voivodeship, Poland
Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie Panstwowy Instytut Badawczy
Warsaw, Masovian Voivodeship, Poland
Szpitale Pomorskie Sp. z o.o. Oddzial Onkologii Klinicznej
Gdynia, Pomeranian Voivodeship, Poland
IP Clinic Sp. z o.o.
Lodz, Łódź Voivodeship, Poland
Hospital Beatriz Ângelo. Hospital de Loures - Oncologia Medica
Loures, Lisbon District, Portugal
Hospital De Vila Franca De Xira E.P.E.
Vila Franca de Xira, Lisbon District, Portugal
IPO Porto FG, EPE
Porto, Madeira, Portugal
C.H. de Vila Nova de Gaia/Espinho - Oftalmologia
Vila Nova de Gaia, Porto District, Portugal
CHUC - Centro Hospitalar e Universitário de Coimbra
Coimbra, Portugal
Unidade Local de Saúde do Algarve, E. P. E.
Faro, Portugal
Instituto Portugues de Oncologia de Lisboa Francisco Gentil - Oncologia Medica
Lisbon, Portugal
ULS Lisboa Ocidental (ULSLO)
Lisbon, Portugal
Hospital CUF Descobertas
Lisbon, Portugal
Unidade Local De Saude De Santo Antonio E.P.E.
Porto, Portugal
Hospital da Luz de Setubal
Setúbal, Portugal
Unidade Local de Saúde de Arrábida
Setúbal, Portugal
Centro Hospitalar de Trás-os-Montes e Alto Douro, EPE
Vila Real, Portugal
Institutul Oncologic Prof Dr Ion Chiricuta Cluj-Napoca
Cluj-Napoca, Cluj, Romania
Oncolab - Medical Oncology
Craiova, Dolj, Romania
Onco Clinic Consult - Ambulatory
Craiova, Dolj, Romania
Centrul de Oncologie Sf. Nectarie
Craiova, Dolj, Romania
Oncomed - Medical Oncology
Timișoara, Timiș County, Romania
Spitalul Clinic Filantropia
Bucharest, Romania
Spitalul Clinic CF Nr 2 Bucuresti
Bucharest, Romania
Memorial Healthcare International
Bucharest, Romania
Radiotherapy Center Cluj
Floreşti, Romania
Institutul Regional de Oncologie Iasi - Medical Oncology
Iași, Romania
National University Hospital
Singapore, Central Singapore, Singapore
OncoCare Cancer Centre
Singapore, North East, Singapore
Raffles Hospital
Singapore, Singapore
Curie Oncology (Farrer)
Singapore, Singapore
Chungbuk National University Hospital
Cheongju-si, Chungcheongbugdo [Ch'ungch'ongbuk-do], South Korea
CHA Bundang Medical Center, CHA University
Seongnam-si, Gyeonggido, South Korea
Gachon University Gil Medical Center
Incheon, Incheon Gwang'yeogsi [Inch'n-Kwangyokshi], South Korea
Severance Hospital, Yonsei University Health System
Seoul, Seoul Teugbyeolsi [Seoul-T'ukpyolshi], South Korea
Asan Medical Center
Seoul, Seoul Teugbyeolsi [Seoul-T'ukpyolshi], South Korea
Gangnam Severance Hospital - Oncology
Seoul, Seoul Teugbyeolsi [Seoul-T'ukpyolshi], South Korea
Korea University Guro Hospital
Seoul, Seoul Teugbyeolsi [Seoul-T'ukpyolshi], South Korea
Korea University Anam Hospital
Seoul, Seoul Teugbyeolsi [Seoul-T'ukpyolshi], South Korea
Ewha Womans University Mokdong Hospital
Seoul, Seoul Teugbyeolsi [Seoul-T'ukpyolshi], South Korea
Inje University Haeundae Paik Hospital
Busan, South Korea
Kyungpook National University Chilgok Hospital
Daegu, South Korea
National Cancer Center
Gyeonggi-do, South Korea
Ajou University Hospital
Gyeonggi-do, South Korea
Seoul National University Hospital
Seoul, South Korea
The Catholic University of Korea, Seoul St. Mary's Hospital
Seoul, South Korea
Ulsan University Hospital
Ulsan, South Korea
Hospital Alvaro Cunqueiro
Vigo, A Coruña, Spain
Hospital Universitario Virgen del Rocío
Seville, Andalusia, Spain
H. Virgen de Valme
Seville, Andalusia, Spain
ICO Badalona-Hospital Germans Trias i Pujol
Badalona, Barcelona, Spain
Hospital Universitari General de Catalunya
Sant Cugat del Vallès, Barcelona, Spain
Hospital de Sant Joan Despi Moises Broggi
Sant Joan Despí, Barcelona, Spain
Hospital Universitario de Canarias
San Cristóbal de La Laguna, Canary Islands, Spain
Hospital Universitario Rey Juan Carlos
Móstoles, Madrid, Spain
Hospital Clínico Universitario Virgen De La Arrixaca
El Palmar, Murcia, Spain
Fundación Instituto Valenciano Oncologia
Valencia, Navarre, Spain
Complexo Hospitalario Universitario A Coruña
A Coruña, Spain
Hospital Universitari Vall D Hebron
Barcelona, Spain
Hospital Clinic De Barcelona - Oncología Médica
Barcelona, Spain
Hospital de La Santa Creu i Sant Pau
Barcelona, Spain
Hospital Universitario Reina Sofia
Córdoba, Spain
Hospital Universitario de Jaén
Jaén, Spain
H.U. Insular Gran Canaria
Las Palmas de Gran Canaria, Spain
H.U Arnau De Vilanova Lleida
Lleida, Spain
Hospital Universitario Lucus Augusti
Lugo, Spain
Hospital Beata Maria Ana
Madrid, Spain
Hospital General Universitario Gregorio Marañón - Oncology
Madrid, Spain
Hospital Universitario Ramón y Cajal
Madrid, Spain
Hospital Clínico San Carlos
Madrid, Spain
Hospital Universitario Fundacion Jimenez Diaz
Madrid, Spain
Hospital Universitario 12 de Octubre
Madrid, Spain
Hospital Universitario La Paz
Madrid, Spain
Hospital Universitario Virgen De La Victoria
Málaga, Spain
Hospital Regional Universitario de Málaga (Hospital Civil)
Málaga, Spain
Hospital Universitario de Santiago
Santiago de Compostela, Spain
Hospital Universitario Virgen de la Macarena - Oncología Médica
Seville, Spain
Hospital Clinico Universitario De Valencia
Valencia, Spain
Hospital Quironsalud Valencia
Valencia, Spain
Hospital Clínico Universitario Lozano Blesa - Oncología Médica
Zaragoza, Spain
Tumor Zentrum Aarau
Aarau, Aargau (de), Switzerland
Kantonsspital Badenv
Baden, Aargau (de), Switzerland
Kantonsspital Baselland
Liestal, Basel-Landschaft (de), Switzerland
Universitätsspital Basel
Basel, Basel-Stadt (de), Switzerland
HOCH Health Ostschweiz - Kantonsspital St.Gallen
Sankt Gallen, Sankt Gallen (de), Switzerland
Centre Hospitalier Universitaire Vaudois (CHUV)Département d'oncologie
Lausanne, Vaud (fr), Switzerland
Kantonsspital Winterthur
Winterthur, Zürich (de), Switzerland
Brust-Zentrum AG Zurich
Zurich, Zürich (de), Switzerland
Inselspital, Universitätsspital Bern
Bern, Switzerland
Hopitaux Universitaires de Geneve (HUG) - Hopital Cantonal
Geneva, Switzerland
Spitaeler Schaffhausen Kantonspital
Schaffhausen, Switzerland
Universitätsspital Zürich
Zurich, Switzerland
Kuang Tien General Hospital - Shalu Xiangshang Division - Hemato-Oncology
Taichung, Taichung, Taiwan
Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation
New Taipei City, Taipei, Taiwan
Taipei Medical University - Shuang Ho Hospital Ministry of Health and Welfare - Hematology & Oncology
New Taipei City, Taipei, Taiwan
Taipei Veterans General Hospital - Hematology
Taipei City, Taipei, Taiwan
National Defense Medical Center (NDMC) - Tri-Service General Hospital - Neihu Branch
Taipei City, Taipei, Taiwan
Koo Foundation Sun Yat-Sen Cancer Center - Hematology
Taipei, Taoyuan, Taiwan
Chang Gung Medical Foundation - LinKou Chang Gung Memorial Hospital - Breast Surgery
Taiyuan, Taoyuan, Taiwan
Changhua Christian Medical Foundation Changhua Christian Hospital
Changhua, Taiwan
China Medical University Hospital - Breast Surgery
Taichung, Taiwan
National Cheng Kung University Hospital
Tainan, Taiwan
Chi Mei Medical Center - Liouying - Oncology
Tainan, Taiwan
National Taiwan University Hospital - Surgery
Taipei, Taiwan
Baskent Universitesi Adana Uygulama ve Arastirma Merkezi
Adana, Adana/ Yuregir, Turkey (Türkiye)
Sakarya Egit ve Aras Hast
Sakarya, Adapazari, Turkey (Türkiye)
Dr Abdurrahman Yurtaslan EAH
Ankara, Ankara/ Yenimahalle, Turkey (Türkiye)
Memorial Ankara Hastanesi
Ankara, Ankara/Cankaya, Turkey (Türkiye)
Ankara City Hospital - Medical Oncology
Ankara, Cankaya/Ankara, Turkey (Türkiye)
Prof. Dr. Suleyman Yalcin Sehir Hastanesi
Kadıköy, Istanbul, Turkey (Türkiye)
VM MedicalPark Pendik Hospital
Istanbul, Istanbul/Pendik, Turkey (Türkiye)
Dokuz Eylul Universitesi - Tip Fakultesi
Balçova, İzmir, Turkey (Türkiye)
Kocaeli Uni Egt ve Uyg Hast
İzmit, Kocaeli, Turkey (Türkiye)
Necmettin Erbakan Universitesi Tip Fakultesi Hastanesi
Konya, Meram/Konya, Turkey (Türkiye)
VM Medical Park Mersin Hastanesi
Mersin, Mersin/Mezitli, Turkey (Türkiye)
Medipol Mega Hospital - Medical Oncology
Istanbul, Samsun, Turkey (Türkiye)
Acibadem Maslak Hospital
Istanbul, Samsun, Turkey (Türkiye)
Acibadem Atasehir Hospital
Istanbul, Samsun, Turkey (Türkiye)
Medical Park Seyhan Hospital
Adana, Seyhan/Adana, Turkey (Türkiye)
Gazi Uni Hast
Ankara, Yenimahalle/Ankara, Turkey (Türkiye)
Adana Sehir Egitim ve Arastirma Hastanesi
Adana, Yüregir, Turkey (Türkiye)
Ankara Etlik Sehir Hastanesi - Tıbbi Onkoloji
Ankara, Turkey (Türkiye)
Hacettepe University Medical Faculty - Medical Oncology
Ankara, Turkey (Türkiye)
Gulhane Training and Research Hospital
Ankara, Turkey (Türkiye)
Ankara Universitesi Tip Fakultesi Cebeci Arastirma Ve Uygulama Hastanesi
Ankara, Turkey (Türkiye)
Adnan Menderes Universitesi - Uygulama ve Arastirma Hastanesi
Aydin, Turkey (Türkiye)
Dicle Universitesi Hastanesi
Diyarbakır, Turkey (Türkiye)
Medical Park Florya Hastanesi
Istanbul, Turkey (Türkiye)
Acibadem Altunizade Hospital
Istanbul, Turkey (Türkiye)
Medical Point Izmir Hospital
Izmir, Turkey (Türkiye)
VM Medical Park Samsun Hospital - Medical oncology
Samsun, Turkey (Türkiye)
Royal Cornwall Hospital (RCH) - Sunrise Centre
Truro, Cornwall, United Kingdom
Whittington Health NHS Trust - Whittington Hospital
London, England, United Kingdom
Cheltenham General Hospital
Cheltenham, Gloucestershire, United Kingdom
Mount Vernon Cancer Centre - Main Site
Northwood, Greater London, United Kingdom
Blackpool Victoria Hospital
Blackpool, Lancashire, United Kingdom
Royal Preston Hospital
Preston, Lancashire, United Kingdom
University College London Hospitals
London, London, City of, United Kingdom
St John's Hospital - NHS Lothian
Livingston, Scotland, United Kingdom
Musgrove Park Hospital
Taunton, Somerset, United Kingdom
Western General Hospital
Edinburgh, United Kingdom
Leeds Cancer Centre
Leeds, United Kingdom
St Bartholomew's Hospital
London, United Kingdom
Maidstone Hospital Kent Oncology Centre
Maidstone, United Kingdom
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT06492616