RecruitingPhase 1NCT06498713

Patient Controlled Administration of Liquid Acetaminophen

Patient Controlled Self-Administration of Oral Liquid Medication: Acetaminophen Trial

Sponsor

Yale University

Enrollment

24 participants

Start Date

Nov 19, 2024

Study Type

INTERVENTIONAL

Conditions

Pain Pain, Postoperative

Summary

This is a proof of concept pilot study investigating the feasibility and acceptability of patient controlled oral medication administration, using the commonly used and low risk medication in the hospital, oral acetaminophen.

Eligibility

Min Age: 18 Years

Inclusion Criteria4

Participants
Adult patients older than 18 years old admitted to SRC for total shoulder and reverse total shoulder arthroplasty
Nurses
The nurse who will administer acetaminophen to a study patient.

Exclusion Criteria15

Participants
Pregnant patient
Patients that cannot swallow pills or cannot take liquid (for example due to risk of aspiration)
Emergency surgery
Chronic pain
On home opioids, any other pain modulating medications including benzodiazepine, Neurontin, ketamine.
Past medical or social history of substance abuse disorder, including ethanol misuse disorder, marijuana misuse disorder
History of any psychiatric disorders including anxiety, depression, any cognitive dysfunction
Any patients who cannot provide informed consents on their own (those who would need Legally Authorized Representatives (LARs) or surrogates)
Liver dysfunction limiting amount of safe oral acetaminophen
baseline hyperbilirubinemia (ex: chronic liver disease, Gilbert's)
patients unable to take PO
Patients with neurologic, neuromuscular, or movement disorders unable to drink from a cup.
Nurses
any nurse who is not involved in the direct care of a study patient, or who is not comfortable with setting up the PCA pump.