RecruitingNot ApplicableNCT06501118

Optimizing Care in Critically Ill at UCHealth by Liberalizing the Target O2 in Mechanically-ventilated ICU Patients

Sponsor

University of Colorado, Denver

Enrollment

3,600 participants

Start Date

Sep 1, 2024

Study Type

INTERVENTIONAL

Conditions

Respiratory Failure Hypoxia Acute Hypoxemic Respiratory Failure Hypoxemia Hypoxic Respiratory Failure Acute Hypoxic Respiratory Failure

Summary

A multimodal educational intervention to target an oxygen saturation target range (SpO2 90-96%) will reduce ventilator length of stay and reduce occult hypoxemia by increased awareness and adherence to a designated oxygen saturation target range.

Eligibility

Min Age: 18 Years

Inclusion Criteria1

Admission to ICU and requiring invasive mechanical ventilation

Exclusion Criteria4

Transferred patients from outside the UCHealth system\*:
Patients with pre-existing disease that requires chronic use of positive pressure ventilation delivered through a tracheostomy\*:
Pregnant women:
Prisoners

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Interventions

OTHEREducation

1\) Standardized materials to discuss the rationale and procedural aspects of the intervention, including details on the specific oxygen target-related modifications to the mechanical ventilation order-set prior to starting the intervention phase.

BEHAVIORALEpic notification alert

An education-based intervention that focuses on mitigating Occult Hypoxemia in mechanically ventilated patients and thus utilizes the same patient population. The second intervention will notify the clinical team to an abnormal laboratory result in real time. This laboratory result is already located in the patient's Epic chart under arterial blood gas (ABG), arterial oxygen saturation (Sa02) Patient level randomization will occur in Epic to as 1. alert (notification) the providers of sustained occult hypoxemia 2. silent alert