RecruitingNCT06503432

The Effects of Programmed Death-ligand 1 on Postoperative Pain for Lung Cancer Patients

Sponsor

Peking University People's Hospital

Enrollment

100 participants

Start Date

Jul 20, 2024

Study Type

OBSERVATIONAL

Conditions

Lung Cancer Postoperative Pain

Summary

The concentration of plasma programmed death-ligand 1(PD-L1) for lung cancer patients before video-assisted thoracoscopic surgery is detected. According to the distribution of plasma concentration, patients are divided into high or low expression of PD-L1. Differences in acute and chronic postoperative pain are compared between two groups of patients. And effects of PD-L1 expresion on postoperative pain in lung cancer patients are explained.

Eligibility

Min Age: 18 YearsMax Age: 80 Years

Plain Language Summary

Simplified for easier understanding

This study looks at how a protein called PD-L1 affects pain levels after surgery for lung cancer. Researchers want to understand whether this immune marker plays a role in how much pain patients feel following minimally invasive (keyhole) chest surgery. **You may be eligible if...** - You are between 18 and 80 years old - You are having keyhole (video-assisted) chest surgery to remove a malignant lung tumor - Your overall health is rated as suitable for surgery (ASA class I–IV) **You may NOT be eligible if...** - You have a history of opioid (strong painkiller) abuse - You have a known psychiatric disorder - Your surgery needs to be converted to open chest surgery or you require intensive care afterward - You are having surgery on more than one area at the same time Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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