RecruitingNCT06503432

The Effects of Programmed Death-ligand 1 on Postoperative Pain for Lung Cancer Patients


Sponsor

Peking University People's Hospital

Enrollment

100 participants

Start Date

Jul 20, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

The concentration of plasma programmed death-ligand 1(PD-L1) for lung cancer patients before video-assisted thoracoscopic surgery is detected. According to the distribution of plasma concentration, patients are divided into high or low expression of PD-L1. Differences in acute and chronic postoperative pain are compared between two groups of patients. And effects of PD-L1 expresion on postoperative pain in lung cancer patients are explained.


Eligibility

Min Age: 18 YearsMax Age: 80 Years

Inclusion Criteria3

  • American Society of Anesthesiologists physical status I-IV (males and females).
  • years of age.
  • Patients undergoing video-assisted thoracoscopic surgery for malignant lung disease.

Exclusion Criteria4

  • History of opioid abuse.
  • Known psychiatric disorders.
  • Unexpected conversion to thoracotomy or transferred to intensive care unit for further treatment.
  • Combined with other surgeries or sites.

Locations(1)

Peking University People's Hospital

Beijing, Beijing Municipality, China

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NCT06503432


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