RecruitingNCT06513273

Observational Study on the Outcome of AML Patients Treated With New Drugs in Real-life (BoxTrial)

Observational GIMEMA Study on the Outcome of Acute Myeloid Leukemia (AML) Patients Treated With New Drugs in Real-life


Sponsor

Gruppo Italiano Malattie EMatologiche dell'Adulto

Enrollment

397 participants

Start Date

Jul 11, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

This multicenter, prospective and retrospective observational study aims to evaluate the use and efficacy of new drugs or their combinations in real-life in a population of adult AML patients.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This observational study is collecting real-world data on how patients with acute myeloid leukemia (AML) respond to newer approved drugs — such as gilteritinib, IDH inhibitors, oral azacytidine, glasdegib, and gemtuzumab ozogamicin — when used outside of controlled clinical trials, in everyday practice. **You may be eligible if...** - You are 18 or older and have been diagnosed with AML (excluding the APL subtype) - You are being treated with one of the newer approved AML drugs (listed above) in standard clinical practice - You have signed informed consent (where required by your institution) **You may NOT be eligible if...** - You are already enrolled in an interventional (experimental treatment) clinical trial - You have APL (M3 AML subtype) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(2)

Ematologia Ente Ecclesiastico Casa Sollievo Della Sofferenza

San Giovanni Rotondo, Italy

UOC Ematologia AOU di SASSARI

Sassari, Italy

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NCT06513273


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