RecruitingNot ApplicableNCT06517589

Process-based Therapy for Difficult-to-treat Anxiety Disorders and Depression

Process-based Therapy vs. Routine-CBT for Difficult-to-treat Anxiety Disorders and Depression

Sponsor

Goethe University

Enrollment

80 participants

Start Date

Jan 29, 2024

Study Type

INTERVENTIONAL

Conditions

Depression Anxiety Disorder

Summary

The aim of this study is to test the relative efficacy of Process-based Therapy compared to traditional CBT delivered in routine practice (r-CBT) for difficult-to-treat anxiety disorders and depression.

Eligibility

Min Age: 18 YearsMax Age: 65 Years

Inclusion Criteria5

A primary DSM-5 diagnosis of depressive or anxiety disorder
At least two unsuccessful attempts of pharmacological or psychological treatment according to the German guidelines for the treatment of depression or anxiety disorders (Arbeitsgemeinschaft der Wissenschaftlichen Medizinischen Fachgesellschaften, AWMF)
Age 18-65 years
Sufficient knowledge of the German language
Participating patients are not required to discontinue medication, but to keep medication constant over the treatment period

Exclusion Criteria8

Increased suicidality
Substance abuse or dependency
Borderline personality disorder
Pervasive developmental disorder
Psychotic disorder
Eating disorder
Bipolar disorder
Severe physical illness

Interventions

OTHERProcess-based Cognitive Behavioral Therapy (PBT)

PBT (20 sessions), intervention planning based on the use of EMA data, feedback of dynamic network analysis and matching of interventions to central nodes of the network.

OTHERCognitive Behavioral Therapy (CBT)

CBT (20 sessions), intervention planning as usual based on manual.