RecruitingNot ApplicableNCT06517589

Process-based Therapy for Difficult-to-treat Anxiety Disorders and Depression

Process-based Therapy vs. Routine-CBT for Difficult-to-treat Anxiety Disorders and Depression


Sponsor

Goethe University

Enrollment

80 participants

Start Date

Jan 29, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The aim of this study is to test the relative efficacy of Process-based Therapy compared to traditional CBT delivered in routine practice (r-CBT) for difficult-to-treat anxiety disorders and depression.


Eligibility

Min Age: 18 YearsMax Age: 65 Years

Plain Language Summary

Simplified for easier understanding

This study is testing a newer psychological approach called Process-Based Therapy (PBT) for people in Germany who have depression or anxiety disorders that have not improved despite trying at least two standard treatments. PBT is a flexible therapy that focuses on the mental processes underlying distress rather than applying a fixed protocol. **You may be eligible if...** - You are 18–65 years old - You have a primary DSM-5 diagnosis of a depressive disorder or anxiety disorder - You have already tried and not responded to at least two different treatments (medication or psychological therapy) following German clinical guidelines - You have a sufficient understanding of the German language - You are willing to keep your current medications stable during the treatment period (you do not need to stop them) **You may NOT be eligible if...** - You have high or active suicidal thoughts - You are currently using substances or alcohol in a way that would interfere with treatment - You have a severe personality disorder or psychotic illness that would require different primary treatment Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERProcess-based Cognitive Behavioral Therapy (PBT)

PBT (20 sessions), intervention planning based on the use of EMA data, feedback of dynamic network analysis and matching of interventions to central nodes of the network.

OTHERCognitive Behavioral Therapy (CBT)

CBT (20 sessions), intervention planning as usual based on manual.


Locations(1)

JWGUniversity

Frankfurt am Main, Hesse, Germany

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NCT06517589


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