Anxiety Disorder Clinical Trials

18 recruiting

Anxiety Disorder Trials at a Glance

216 actively recruiting trials for anxiety disorder are listed on ClinicalTrialsFinder across 6 cities in 35 countries. The largest study group is Not Applicable with 136 trials, with the heaviest enrollment activity in Boston, New York, and Houston. Lead sponsors running anxiety disorder studies include Massachusetts General Hospital, Karolinska Institutet, and National Institute of Mental Health (NIMH).

Browse anxiety disorder trials by phase

Treatments under study

About Anxiety Disorder Clinical Trials

Looking for clinical trials for Anxiety Disorder? There are currently 18 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Anxiety Disorder trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Anxiety Disorder clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 216 trials

Recruiting
Phase 2

Study of Neuro-Cognitive Correlates of Pediatric Anxiety Disorders

Major Depressive DisorderAnxiety Disorders
National Institute of Mental Health (NIMH)3,500 enrolled1 locationNCT00018057
Recruiting

Development of Magnetic Resonance Imaging Techniques for Studying Mood and Anxiety Disorders

Anxiety DisordersMood Disorders
National Institute of Mental Health (NIMH)390 enrolled1 locationNCT00397111
Recruiting
Not Applicable

Text Message Safety Behavior Fading for Pathological Worry

WorryingAnxietyGeneralized Anxiety Disorder (GAD)
Florida State University300 enrolled1 locationNCT07391020
Recruiting
Not Applicable

The Impact of Melatonin Lotion on Sleep and Mental Health

Sleep ProblemsDepressive Disorder and Anxiety Disorders
University of Redlands60 enrolled1 locationNCT06768749
Recruiting
Not Applicable

Enhancing Engagement by Integrating Goals and Concerns That Matter to Patients

Anxiety DisordersDepression Disorders
Dartmouth-Hitchcock Medical Center2,448 enrolled6 locationsNCT06898593
Recruiting
Phase 3

Fasedienol Nasal Spray for the Acute Treatment of Anxiety in Adults With Social Anxiety Disorder (PALISADE-4)

Social Anxiety Disorder (SAD)
VistaGen Therapeutics, Inc.236 enrolled26 locationsNCT06615557
Recruiting
Not Applicable

DINO RCT - Treating Anxiety in Children With Autism

Autism Spectrum DisorderAnxiety Disorders
Hugo W. Moser Research Institute at Kennedy Krieger, Inc.70 enrolled1 locationNCT06066983
Recruiting
Not Applicable

Personalized Digital Treatment for Adolescent Anxiety: A Feasibility Trial

Anxiety Disorders
Helse Stavanger HF46 enrolled2 locationsNCT07145307
Recruiting
Not Applicable

Closed-Loop Neurofeedback Targeting the Left Dorsolateral Prefrontal Cortex for Cardiac Autonomic Modulation in Coronary Artery Disease With Anxiety

Coronary Heart Disease (CHD)Anxiety Disorders
Shenyang Medical College56 enrolled1 locationNCT07244484
Recruiting
Not Applicable

Closed-Loop Neurofeedback Targeting the Right Dorsolateral Prefrontal Cortex for Cardiac Autonomic Modulation in Coronary Artery Disease With Anxiety

Coronary Heart Disease (CHD)Anxiety Disorders
Shenyang Medical College56 enrolled1 locationNCT07238920
Recruiting

DLPFC and Sympathetic Reactivity in RPL With Anxiety

Anxiety DisorderRecurrent Pregnancy Loss Without Current Pregnancy
Shenyang Medical College50 enrolled2 locationsNCT07045818
Recruiting
Not Applicable

tVNS and Approach-Avoidance Behavior in Anhedonia and Anxiety

Healthy ParticipantsAnxiety Disorders (With High Anxiety Symptoms)Depressive Disorders (With High Anhedonia Symptoms)+1 more
Dr. Nils B. Kroemer104 enrolled1 locationNCT07476469
Recruiting
Not Applicable

The STEP-MIED Trial: Digital Stepped-Care for Emotional Disorders

Depressive DisorderAnxiety DisordersObsessive-Compulsive Disorder+1 more
Peking University464 enrolled1 locationNCT07458100
Recruiting
Not Applicable

High-Intensity, Low-Frequency Periodic rTMS Over the Right Dorsolateral Prefrontal Cortex on Cardiac Autonomic Regulation in Women With Recurrent Pregnancy Loss and Anxiety

Anxiety DisordersRecurrent Pregnancy Loss
Shenyang Jinghua Hospital55 enrolled3 locationsNCT06968026
Recruiting

Phenotypic Exploration During Sensory Stimulation in an Acoustic Chamber

EpilepsyAnxietyDepression Anxiety Disorder
Centre Hospitalier St Anne320 enrolled1 locationNCT07544563
Recruiting
Not Applicable

A Preventive Behavioral Intervention for Young Adults With Psychotic Experiences

Psychotic DisordersAnxiety DisordersMood Disorders
Massachusetts General Hospital192 enrolled1 locationNCT06929442
Recruiting
Not Applicable

Family Spirit Strengths

Mental Health IssueDepressive SymptomsAnxiety Disorders and Symptoms+1 more
Johns Hopkins Bloomberg School of Public Health188 enrolled3 locationsNCT05836090
Recruiting
Phase 3

Study to Evaluate the Efficacy and Safety of VQW-765 for the On-Demand Treatment of Social Anxiety Disorder

Social Anxiety Disorder (SAD)
Vanda Pharmaceuticals500 enrolled29 locationsNCT07221578
Recruiting

Evaluation of Patients With Mood and Anxiety Disorders and Healthy Volunteers

DepressionHealthy VolunteersAnxiety Disorders+2 more
National Institute of Mental Health (NIMH)16,000 enrolled1 locationNCT00024635
Recruiting
Phase 2

Gaze-Contingent Music Therapy Augmentation of CBT for Pediatric Anxiety

Anxiety DisordersPsychiatric Disorders
National Institute of Mental Health (NIMH)150 enrolled1 locationNCT06595953