Anxiety Disorder Clinical Trials

239 recruitingLast updated: June 18, 2026

There are 239 actively recruiting anxiety disorder clinical trials across 36 countries. Studies span Not Applicable, Phase 2, Phase 3, Phase 4, Phase 1. Top locations include Boston, Massachusetts, United States, New York, New York, United States, Houston, Texas, United States. Updated daily from ClinicalTrials.gov.


Anxiety Disorder Trials at a Glance

239 actively recruiting trials for anxiety disorder are listed on ClinicalTrialsFinder across 6 cities in 36 countries. The largest study group is Not Applicable with 149 trials, with the heaviest enrollment activity in Boston, New York, and Houston. Lead sponsors running anxiety disorder studies include Massachusetts General Hospital, Karolinska Institutet, and National Institute of Mental Health (NIMH).

Browse anxiety disorder trials by phase

Treatments under study

About Anxiety Disorder Clinical Trials

Looking for clinical trials for Anxiety Disorder? There are currently 20 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Anxiety Disorder trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Anxiety Disorder clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 239 trials

Recruiting
Phase 2

Study to Assess Adverse Events and Change in Disease Activity When Oral ABBV-932 is Added to Antidepressant Therapies in Adult Participants With Generalized Anxiety Disorder

Generalized Anxiety Disorder (GAD)
AbbVie315 enrolled52 locationsNCT06846320
Recruiting

Evaluation of Patients With Mood and Anxiety Disorders and Healthy Volunteers

DepressionHealthy VolunteersAnxiety Disorders+2 more
National Institute of Mental Health (NIMH)16,000 enrolled1 locationNCT00024635
Recruiting
Phase 2

Gaze-Contingent Music Therapy Augmentation of CBT for Pediatric Anxiety

Anxiety DisordersPsychiatric Disorders
National Institute of Mental Health (NIMH)150 enrolled1 locationNCT06595953
Recruiting
Not Applicable

Development of a Transdiagnostic Intervention for Adolescents at Risk for Serious Mental Illness

Depressive DisorderPsychotic DisordersAnxiety Disorders+1 more
Massachusetts General Hospital70 enrolled1 locationNCT05962879
Recruiting
Not Applicable

Feasibility Study of UP-A-AST Parent Group for Adolescents With Autism and Co-occurring Anxiety/Depression

Depressive DisorderAnxiety DisordersAutistic Spectrum Disorder
Sahlgrenska University Hospital72 enrolled1 locationNCT07637799
Recruiting
Not Applicable

Experimental Evidence of the Impact of Parental Income on Child Mental Health and Neuroimmune Function

PsychopathologyAnxiety DisordersMental Disorders+3 more
Northwestern University500 enrolled1 locationNCT07641244
Recruiting
Not Applicable

CO2 Reactivity as a Biomarker of Non-Response to Exposure-Based Therapy

Post Traumatic Stress DisorderObsessive-Compulsive DisorderSocial Anxiety Disorder+2 more
Jasper A. Smits600 enrolled2 locationsNCT05467683
Recruiting

Development of Magnetic Resonance Imaging Techniques for Studying Mood and Anxiety Disorders

Anxiety DisordersMood Disorders
National Institute of Mental Health (NIMH)390 enrolled1 locationNCT00397111
Recruiting
Not Applicable

Personalized AI-Driven Models in Cognitive Behavioral Therapy for Anxiety

Generalized Anxiety Disorder (GAD)
University of Southern California140 enrolled1 locationNCT07430800
Recruiting
Not Applicable

Neurofeedback Enhanced Cognitive Reappraisal Training - Phase 4

AnxietySocial Anxiety DisorderGeneralized Anxiety Disorder+1 more
University of Michigan110 enrolled1 locationNCT06563310
Recruiting
Not Applicable

Cognitive Behavior Therapy in Psychiatric Inpatient Care

Depression, Anxiety DisordersPsychiatric Inpatients
Region Stockholm204 enrolled1 locationNCT07503951
Recruiting
Not Applicable

RXWell to Decrease Post-Operative Opioid Use in Total Knee or Hip Arthroplasty

Anxiety DepressionDepressionAnxiety+3 more
University of Pittsburgh150 enrolled3 locationsNCT05658796
Recruiting

Identification and Molecular Characterisation of Urban-environmental Stress Patterns Affecting Mental Illness

Major Depressive Disorder (MDD)Anxiety DisorderAlcohol Use Disorder (AUD)
Huashan Hospital680 enrolled3 locationsNCT07571226
Recruiting
Not Applicable

Safety Behavior Fading Versus Progressive Muscle Relaxation for Appearance Concerns

Eating DisordersSocial Anxiety DisorderBody Dysmorphic Disorder
Florida State University300 enrolled1 locationNCT07589621
Recruiting
Not Applicable

Clinical Study Evaluating Pharmacogenomics-informed Pharmacotherapy Versus Dosing as Usual in Psychiatric Disorders

Psychotic DisordersAnxiety DisordersMood Disorders
Parnassia Groep2,500 enrolled9 locationsNCT05656469
Recruiting
Not Applicable

Computer - Based Treatment for Social Anxiety Disorder

Social Anxiety Disorder
New York State Psychiatric Institute80 enrolled1 locationNCT04663724
Recruiting
Phase 2

Study of Neuro-Cognitive Correlates of Pediatric Anxiety Disorders

Major Depressive DisorderAnxiety Disorders
National Institute of Mental Health (NIMH)3,500 enrolled2 locationsNCT00018057
Recruiting
Phase 3

Study to Evaluate the Efficacy and Safety of VQW-765 for the On-Demand Treatment of Social Anxiety Disorder

Social Anxiety Disorder (SAD)
Vanda Pharmaceuticals500 enrolled30 locationsNCT07221578
Recruiting
Not Applicable

Adaptation of Individual Dialectical Behavior Therapy Intervention for Transdiagnostic Treatment of Emotional Disorders

Depressive DisorderAnxiety Disorder
Mackay Memorial Hospital250 enrolled1 locationNCT05989451
Recruiting
Not Applicable

Right Prefrontal Autonomic Mapping in Recurrent Pregnancy Loss With Comorbid Anxiety

Anxiety DisordersRecurrent Pregnancy Loss
Shenyang Jinghua Hospital55 enrolled3 locationsNCT06968026