RecruitingNCT06528418

Identification of Multiple Pulmonary Diseases Using Volatile Organic Compounds Biomarkers in Human Exhaled Breath

Exploration and Study on the Identification of Various Pulmonary Diseases Using Volatile Organic Compounds Biomarkers in Human Exhaled Breath

Sponsor

ChromX Health

Enrollment

10,000 participants

Start Date

Jun 30, 2024

Study Type

OBSERVATIONAL

Conditions

Lung Cancer Lung Infection COPD Bronchial Asthma Pulmonary Embolism Interstitial Lung Disease Pulmonary Fibrosis Bronchiectasis Bronchitis Pulmonary Arterial Hypertension Pulmonary Tuberculosis Pulmonary Abscess Emphysema Lung Injury Cystic Fibrosis of the Lung Preserved Ratio Impaired Spirometry

Summary

The goal of this observational study is to develop an advanced expiratory algorithm model utilizing exhaled breath volatile organic compound (VOC) marker molecules. This model aims to accurately diagnose mutiple pulmonary diseases. The primary objectives it strives to accomplish are: 1. To assess the diagnostic accuracy of an exhaled breath VOC-assisted diagnostic artificial intelligence (AI) model in diagnose several common pulmonary diseases. 2. To assess the diagnostic accuracy of an exhaled breath VOC-assisted diagnostic artificial intelligence (AI) model in diagnose more pulmonary diseases.

Eligibility

Min Age: 18 YearsMax Age: 100 Years

Plain Language Summary

Simplified for easier understanding

This study is investigating whether chemicals in a person's exhaled breath (called volatile organic compounds) can be used to detect and identify different types of lung disease. It aims to develop a simple, non-invasive breath test that can distinguish between conditions like lung cancer, COPD, and pneumonia. **You may be eligible if...** - You are 18 years or older - You have a confirmed diagnosis of a lung disease (based on CT imaging and clinical evaluation) - You are able to provide digital copies of your CT imaging **You may NOT be eligible if...** - You do not have a clear clinical lung disease diagnosis - You are unable to provide the required imaging data - You have conditions that might interfere with breath sample collection Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

OTHERGas chromatography-mass spectrometry(GC-MS) and micro Gas Chromatography-photoionisation detector (μGC-PID) system

Exhaled breath samples from these participants will be collected and analyzed to detect volatile organic compound molecules in human exhaled breath by GC-MS and μGC-PID

Locations(1)

The First Affiliated Hospital of Guangzhou Medical University

Guangzhou, Guangdong, China

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT06528418

Related Trials

dEtection of rheumAtoid aRthritis - Interstitial Lung dIseasE by Thoracic ultRasound

NCT062356451 location

Molecular Analysis of Endoscopic Cytology Samples Supernatant in Pulmonary Nodules

NCT053069121 location

Standard Follow-up Program (SFP) for Lung Cancer Patients Treated With Radiotherapy or Chemoradiation

NCT024217181 location

Spironolactone for Pulmonary Arterial Hypertension

NCT017126201 location

The AIRTIVITY™ Study: A Study to Find Out Whether BI 1291583 Helps People With Bronchiectasis

NCT06872892494 locations