RecruitingNot ApplicableNCT06534957

Online Mindfulness-based Stress Reduction for Patients Receiving Chemotherapy

Online Mindfulness-based Stress Reduction Intervention for Patients With Breast Cancer Receiving Chemotherapy

Sponsor

Medicos e Investigadores en la Lucha contra el Cancer de Mama

Enrollment

200 participants

Start Date

Sep 2, 2025

Study Type

INTERVENTIONAL

Conditions

Breast Cancer Stress

Summary

The goal of this prospective, waitlist-controlled, 1:1 randomized study is to evaluate if an online mindfulness-based stress reduction (MBSR) intervention reduces treatment-related stress levels among patients with breast cancer receiving chemotherapy. The main questions it aims to answer are: * Does an online MBSR intervention reduce stress levels (measured through the Perceived Stress Scale) among participants? * Does an online MBSR intervention reduce anxiety, depression, insomnia, fatigue, nausea, diarrhea, constipation, pain, and peripheral neuropathy (measured through the PRO-CTCAE of the National Cancer Institute) among participants? Researchers will compare the online MBSR intervention to no intervention to see if online MBSR reduces treatment-related stress. Participants will: * Participate in an online MBSR intervention or no intervention for 6 weeks * Answer the study surveys at baseline, 7 weeks, and 11 weeks of follow-up

Eligibility

Sex: FEMALEMin Age: 18 Years

Inclusion Criteria8

Female sex
Age ≥18 years
Diagnosis of non-metastatic breast cancer
Plan to start neoadjuvant or adjuvant chemotherapy in \<4 weeks
Internet access at home or in their mobile phone
Availability to participate in the online MBSR intervention for 6 weeks
Availability to answer the study surveys
Provision of signed informed consent

Exclusion Criteria3

Disease recurrence
Current meditation or mindfulness practice
Inability to read or write

Interventions

OTHEROnline mindfulness-based stress reduction

The online MBSR intervention sessions will be available in a website created specifically for this purpose, where each pre-recorded session will be uploaded so that each patient can begin the intervention at the same time as their chemotherapy regimen. Each session will last approximately 1 hour, for a total of 6 sessions. The topics that will be covered in these sessions include: mindfulness overview, stress and suffering, emotional regulation, meditation, management of stressful situations, self-compassion and acceptance. Participants will watch 1 session per week following the order that will be indicated on the website; patients will be encouraged to watch the sessions during their chemotherapy infusions. During these sessions, patients will be instructed in mindfulness practice and will perform targeted exercises to promote complete consciousness, including mindful body awareness (body scan), gentle yoga exercises, and meditation.