RecruitingPhase 1Phase 2NCT06543979

Anorectal Manometery in Pediatric Chronic Refractory Constipation

The Diagnostic Value of Anorectal Manometry in Pediatric Chronic Refractory Constipation With or Without Fecal Incontinence


Sponsor

Ain Shams University

Enrollment

60 participants

Start Date

Sep 7, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

Anorectal manometry and high-resolution anorectal manometry (HRAM) are becoming the investigation of choice for understanding the pathophysiology of chronic constipation with or without fecal incontenance in children in many institutions. In high resolution anorectal manometery we are able to gain information whether the symptoms are related to sphincter dysfunction, impaired sensation, or pelvic floor dyssynergia


Eligibility

Min Age: 4 YearsMax Age: 16 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a procedure called biofeed back sessions, a procedure called botox injection, and others for people with chronic constipation. The study is currently recruiting participants at 1 location. People eligible for this study include aged 4 Years to 16 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGlubiprostone , single arm

laxative

PROCEDUREbiofeed back sessions

Biofeedback for participants with dyssynergic defecation and participants with reduced rectal sensations

PROCEDUREbotox injection

Botulinum toxin injection for participants suffering from elevated anal canal pressure


Locations(1)

Ain shams university

Cairo, Egypt

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NCT06543979


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