Exploring the Potential Benefits of Probiotic Yogurt
Exploring the Potential Benefits of High-activity Probiotic Yogurt: a Randomized, Double-blind, Placebo-controlled Trial
Wecare Probiotics Co., Ltd.
84 participants
Feb 25, 2025
INTERVENTIONAL
Conditions
Summary
This study aims to evaluate the effect of a high-activity probiotic yogurt on improving symptoms of chronic constipation, observing its regulatory effects on the gut microbiota and the incidence of adverse reactions in study participants over a 21-day intervention period.
Eligibility
Inclusion Criteria3
- Meet the Rome IV diagnosis criteria for chronic constipation;
- Patients who are able to understand clinical studies and are committed to complying with study requirements and procedures;
- Age 18-65. -
Exclusion Criteria10
- Systemic (diabetes, autoimmune diseases, cancer), gastrointestinal or liver diseases known to be associated with alterations in the gut microbiota;
- Patients who are pregnant or lactating;
- have taken antimicrobials, probiotics, or drugs that inhibit stomach acid or gastrointestinal motility in the past 6 weeks;
- Patients who changed their diet type during the study;
- Patients who are allergic or intolerant to any component of the investigational product formulation;
- Patients with cardiovascular, cerebrovascular, liver, kidney and hematopoietic system and other serious diseases and endocrine diseases, mental patients;
- Stop taking the tested sample or add other drugs in the middle, unable to judge the efficacy or incomplete data;
- short-term use of objects related to the function of the test, affecting the judgment of the result;
- have been dieting, exercising excessively, taking weight loss medications or taking medications that may affect appetite in the past 3 months;
- Current or past excessive use of alcohol, drugs, or supplements that may cause intestinal dysfunction or interfere with the evaluation of the efficacy of the study product -
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Interventions
The intervention phase of this study will last 3 weeks, and each participant will make 3 visits (week 0, week 1, week 3).
The intervention phase of this study will last 3 weeks, and each participant will make 3 visits (week 0, week 1, week 3).
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06847919