Single Session vs Multiple-Session Panretinal Photocoagulation for Treatment of Proliferative Diabetic Retinopathy

This study is comparing two approaches to panretinal photocoagulation (PRP) — a laser treatment for a serious eye complication of diabetes called proliferative diabetic retinopathy (PDR). PDR occurs when abnormal blood vessels grow in the retina and can lead to vision loss. The study is comparing doing all the laser treatment in a single session versus spreading it out over multiple sessions to see which approach is safer and equally effective. **You may be eligible if...** - You are over 18 years old with type 1 or type 2 diabetes - You have been newly diagnosed with proliferative diabetic retinopathy (PDR) - You have usable vision in the study eye (visual acuity 0.1 or better on the Snellen chart) - Your retina is not too swollen (OCT thickness under 300 micrometers) - Your pupil can be dilated adequately and the media is clear enough for laser treatment **You may NOT be eligible if...** - You have had eye surgery in the last 4 months or have surgery planned in the next 3 months - You have diabetic macular edema affecting the center of your vision - You have previously received PRP, injections into the eye, or macular laser in this eye - You take medications known to cause macular edema - You have a condition making office laser treatment unsafe or very difficult Talk to your doctor to see if this trial is right for you.