RecruitingNot ApplicableNCT06549348

Radiation Free Study


Sponsor

Philips Clinical & Medical Affairs Global

Enrollment

182 participants

Start Date

Jul 3, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

This is a prospective, randomized, unblinded, multi-center study. Sites were selected from different geographies (EU and US) with different clinical practice to ensure the results are more generalizable. Primary objective is to demonstrate that the average procedure fluoroscopy time using LumiGuide is lower compared to conventional fluoroscopy guidance in Fenestrated Endovascular Aortic Repair (FEVAR)


Eligibility

Min Age: 18 Years

Inclusion Criteria4

  • Subject will be undergoing a primary Fenestrated Endovascular Aortic Repair (FEVAR) procedure (including subjects with prior infrarenal EVAR or open repair) that includes the incorporation of visceral arteries into the repair.
  • Subject is able to give informed consent and is 18 years of age or older, or of legal age to give informed consent per state or national law.
  • Subject has a life expectancy of at least 2 years
  • Target vessels to be included are the Celiac Trunk, Superior Mesenteric Artery and Renal Arteries

Exclusion Criteria8

  • Subjects undergoing an endovascular procedure that include branches or iliac branched devices (IBD) in the repair
  • Subject treated for re-intervention / staged procedure post-primary FEVAR procedure
  • Subjects intended to be treated for more than 4 target vessels (not counting the contralateral gate)
  • Subject treated for an emergent (<24hrs after emergence) procedure
  • Subject with connective tissue disorder eg, Marfan's or Ehlers Danlos Syndrome
  • Subject with contrast allergies
  • Subject participates in a potentially confounding drug or device trial during the course of the study. Co-enrollment in concurrent trials may be allowed provided that pre-approval is obtained from Philips.
  • Subject unwilling or unable to comply with the protocol unable to understand verbal and/or written informed consent

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Interventions

RADIATIONMeasure average procedure fluoroscopy time using LumiGuide and conventional fluoroscopy guidance

Fenestrated Endovascular Aortic Repair (FEVAR) procedure done with either LumiGuide or conventional fluoroscopy guidance


Locations(9)

University of Alabama

Birmingham, Alabama, United States

University of Massachusetts

Worcester, Massachusetts, United States

University of Pennsylvania

Philadelphia, Pennsylvania, United States

University of Texas Southwestern Medical Center

Dallas, Texas, United States

UZ Gent

Ghent, Belgium

Rigshospitalet University Hospital

Copenhagen, Denmark

Hôpital Universitaire Pitié-Salpêtrière

Paris, France

UMC Maastricht

Maastricht, Netherlands

Guys & St Thomas

London, United Kingdom

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NCT06549348


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