RecruitingPhase 3NCT06560255

Fish Oil in pREgnancY for Personalized Prevention of Early Childhood Asthma

Fish Oil in pREgnancY for Personalized Prevention of Early Childhood Asthma (FREYA)


Sponsor

Professor Klaus Bønnelykke

Enrollment

2,000 participants

Start Date

Dec 20, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The overall aim of the study is to develop a nutritional preventive fish oil supplementation strategy in pregnancy for early childhood asthma/persistent wheeze during the first three years of life as we hypothesize that both supplementations in higher doses than recommended could reduce the risk of disease development.


Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 45 Years

Inclusion Criteria4

  • Pregnant Danish women before week 26 with blood levels of EPA+DHA below 4.7% of total fatty acids
  • No planned use of fish oil supplementations
  • No endocrine-, heart-, kidney- or auto-immune disorders
  • No disorders requiring treatment with blood thinning medication

Interventions

OTHERRape seed oil

Oral intake of 4 capsules per day from week 22-26 in pregnancy to 1 week after delivery

DIETARY_SUPPLEMENTn-3 fatty acid

Oral intake of 4 capsules per day from week 22-26 in pregnancy to 1 week after delivery


Locations(1)

Copenhagen University Hospital of Copenhagen

Gentofte Municipality, Denmark

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NCT06560255


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