RecruitingPhase 3NCT06570889

VItamin D in pregnanCy for prevenTion Of eaRlY Childhood Asthma

VItamin D in pregnanCy for prevenTion Of eaRlY Childhood Asthma (VICTORY)

Sponsor

Professor Klaus Bønnelykke

Enrollment

2,000 participants

Start Date

Dec 20, 2024

Study Type

INTERVENTIONAL

Conditions

Asthma Fractures, Bone Allergy Eczema Respiratory Tract Infections Gastrointestinal Infection Croup Wheezing Development, Child Cognition Disorders in Children Psychiatric Diagnosis

Summary

The overall aim of the study is to develop a nutritional preventive vitamin D supplementation strategy in pregnancy for early childhood asthma/persistent wheeze during the first three years of life as we hypothesize that supplementation in higher doses than recommended could reduce the risk of disease development.

Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 45 Years

Plain Language Summary

Simplified for easier understanding

This trial tests whether vitamin D supplementation during pregnancy can help prevent asthma in young children born to mothers with higher omega-3 fatty acid levels. You may be eligible if... - You are a pregnant Danish woman before 26 weeks of pregnancy - Your blood EPA+DHA (omega-3 fatty acids) levels are above 4.7% of total fatty acids - You are not currently taking more than the recommended 400 IU/day of vitamin D You may NOT be eligible if... - You have an endocrine, heart, kidney, or autoimmune disorder - You take blood-thinning medications Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIETARY_SUPPLEMENTCholecalciferol D3

Oral intake of 1 capsule per day from week 22-26 in pregnancy to 1 week after delivery

OTHEROlive oil

Oral intake of 1 capsule per day from week 22-26 in pregnancy to 1 week after delivery

Locations(1)

Copenhagen University Hospital of Copenhagen

Gentofte Municipality, Denmark

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NCT06570889

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